台大食品科技研究所

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潘 敏雄
专任教师
职称 特聘教授兼所长
姓名 潘 敏雄
联络电话 02-3366-4133
电子邮件 mhpan@ntu.edu.tw
学历 国立台湾大学医学院生化学研究所 博士( 2000 )
研究专长 食品化学、 保健与机能性食品、疾病化学预防
个人网址 http://panmhlab1.wixsite.com/pan-mhlab
2021 Hsiao, TH, Wang, YH, Lin WS, Cheng, YC, Kalyanam, N, Ho, CT, Pan, MH*. Molecular mechanisms of the anti-obesity properties of Agardhiella subulata in mice fed a high-fat diet. Journal of Agricultural and Food Chemistry. 2021. doi: 10.1021/acs.jafc.1c01117
2021 Tung, YC, Shih, YA, Kalyanam, N, Ho, CT, Cheng, AC, Pan, MH*. Coleus forskohlii and Garcinia indica extracts attenuated lipid accumulation by regulating energy metabolism and modulating gut microbiota in obese mice. Food Research International. 2021. 142: 110143.
2021 Chi, HL, Yeh, AI, Pan, MH, Chen, SH*. Physicochemical properties and film formation of the chitin hydrocolloid fabricated by a novel green process. Journal of Applied Polymer Science. 2021. e50762.
2021 Lien, KW, Pan, MH, Ling, MP*. Levels of heavy metal cadmium in rice (Oryza sativa L.) produced in Taiwan and probabilistic risk assessment for the Taiwanese population. Environmental Science and Pollution Research. 2021. doi: 10.1007/s11356-020-11902-w.
2021 Chen, WJ*, Tsai, JH, Hsu, LS, Lin, CL, Hong, HM, Pan, MH*. Quercetin blocks the aggressive phenotype of triple-negative breast cancer by inhibiting IGF1/IGF1R-mediated EMT program. Journal of Food & Drug Analysis. 2021, 29(1):98-112.
2020 Lee, PS, Chiou, YS, Chou, PY, Kalyanam, N, Ho, CT, Pan, MH*. 3′-Hydroxypterostilbene inhibits 7,12-dimethylbenz[a]anthracene (DMBA)/12-O-tetradecanoylphorbol-13-acetate (TPA)-induced mouse skin carcinogenesis. Phytomedicine. 2020. 3(81):153432.
2020 Lin, WS, Lai, YJ, Kalynam, N, Ho, CT, Pan, MH*. S‐allylcysteine Inhibits PhIP/DSS‐induced Colon Carcinogenesis Through Mitigating Inflammation, Targeting Keap1, and Modulating Microbiota Composition in Mice. Molecular Nutrition and Food Research. 2020. Doi: 10.1002/mnfr.202000576.
2020 Chou, YC, Ho, PY, Chen, WJ, Wu, SH, Pan, MH*. Lactobacillus fermentum V3 ameliorates colitis-associated tumorigenesis by modulating the gut microbiome. American Journal of Cancer Research. 2020. 10(4):1170-1181.
2020 Koh, YC, Lin, YC, Lee, PS, Lu, TJ, Lin, KY, Pan, MH*. A multi-targeting strategy to ameliorate high-fat-diet- and fructose-induced (western diet-induced) non-alcoholic fatty liver disease (NAFLD) with supplementation of a mixture of legume ethanol extracts. Food & Function. 2020. 11(9): 7545-7560.
2020 Tung, YC, Liang, ZR, Chou, SF, Ho, CT, Kuo, YL, Cheng, KC, Lu, TJ, Chang, YC, Pan, MH*. Fermented Soy Paste Alleviates Lipid Accumulation in the Liver by Regulating the AMPK Pathway and Modulating Gut Microbiota in High-Fat-Diet-Fed Rats. Journal of Agricultural and Food Chemistry. 2020. 68(35): 9345-9357.
2020 Hsiao, YH, Ho, CT, Pan, MH*. Bioavailability and health benefits of major isoflavone aglycones and their metabolites. Journal of Functional Foods. 2020. 74:104164.
2020 Lien, KW, Ling, MP, Pan, MH*. Probabilistic risk assessment of patulin in imported apple juice and apple‐containing beverages in Taiwan. Journal of the Science of Food and Agriculture. 2020. 100(13):4776-4781.
2020 Lai, CS, Ho, CT, Pan, MH*. The Cancer Chemopreventive and Therapeutic Potential of Tetrahydrocurcumin. Biomolecules. 2020. 10(6):831.
2020 Wang, YJ, Chen, YY, Hsiao, CM, Pan, MH, Wang, BJ, Chen, YC, Ho, CT, Huang, KC, Chen, RJ. Induction of Autophagy by Pterostilbene Contributes to the Prevention of Renal Fibrosis via Attenuating NLRP3 Inflammasome Activation and Epithelial-Mesenchymal Transition. Frontiers in Cell and Developmental Biology. 2020. 8:436.
2020 Lee, PS, Chiou, YS, Nagabhushanam, K, Ho, CT, Pan, MH*. 3′-Hydroxypterostilbene Potently Alleviates Obesity Exacerbated Colitis in Mice. Journal of Agricultural and Food Chemistry. 2020. doi: 10.1021/acs.jafc.0c01782.
2020 Cheng, AC, Jiang, WR, Hsiao, YH, Badmaev, V, Ho, CT, Yu, RC, Pan, MH*. Promoting effect of Se-allylselenocysteine on 7,12-dimethylbenz[a]anthracene (DMBA)/12-O-tetradecanoylphorbol-13-acetate (TPA)-induced skin tumorigenesis. Journal of Food Bioactives, 2020. 9.
2020 Lin, WS, Leland, JV, Ho, CT*, Pan, MH*. Occurrence, bioavailability, anti-inflammatory and anti-cancer effects of pterostilbene. Journal of Agricultural and Food Chemistry. 2020. doi: 10.1021/acs.jafc.9b07860
2020 Chou, YC, Li, S, Ho, CT, Pan, MH*. Preparation and evaluation of self-microemulsifying delivery system containing 5-demethyltangeretin on inhibiting xenograft tumor growth in mice. International Journal of Pharmaceutics. 2020. 579:119134.
2020 Koh, YC, Ho, CT, Pan, MH*. Recent advances in cancer chemoprevention with phytochemicals. Journal of Food and Drug Analysis. 2020. 28(1):14-37.
2019 Pan, MH*, Koh, YC, Lee, TL, Wang, B, Chen, WK, Nagabhushanam, K, Ho, CT. Resveratrol and Oxyresveratrol Activate Thermogenesis via Different Transcriptional Coactivators in High-Fat Diet-Induced Obese Mice. Journal of Agricultural and Food Chemistry. 2019. 67(49):13605-13616
2019 Lin, ZH, Chan, FY, Pan, MH, Tung, YC, Su, ZY. Aged Citrus Peel (Chenpi) Prevents Acetaminophen-Induced Hepatotoxicity by Epigenetically Regulating Nrf2 Pathway. The American Journal of Chinese Medicine. 2019. 47 (8):1833-1851.
2019 Thang, SK., Chen, PY., Gao, WY., Wu, MJ., Pan, MH., Yen, JH. Xanthohumol Suppresses NPC1L1 Gene Expression through Downregulation of HNF-4α and Inhibits Cholesterol Uptake in Caco-2 Cells. Journal of Agricultural and Food Chemistry. 2019. 67(40):11119-11128.
2019 Lee, PS., Teng, CY., Hsieh, KF., Chiou, YS., Wu, JC., Lu, TJ., Pan, MH*. Adzuki Bean Water Extract Attenuates Obesity by Modulating M2/M1 Macrophage Polarization and Gut Microbiota Composition. Molecular Nutrition and Food Research. 2019. 63(23): e1900626.
2019 Tian, X., Guo, S., Zhang, S., Lee, PS., Wang, T., Ho, CT., Pan, MH., Bai, N. Chemical characterization of main bioactive constituents in Paeonia ostii seed meal and GC‐MS analysis of seed oil. Journal of Food Biochemistry. 2019. e13088.
2019 Pan, MH*, Li, MY., Tsai, ML., Pan, CY., Badmaev, V., Ho, CT., and Lai, CS*. A mixture of citrus polymethoxyflavones, green tea polyphenols and Lychee extracts attenuates adipogenesis in 3T3-L1 adipocytes and obesity-induced adipose inflammation in mice. Food & Function. 2019. DOI: 10.1039/C9FO02235J.
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2019 Hung, WL., Ho, CT., Pan, MH*. Targeting the NLRP3 inflammasome in Neuroinflammation: Health Promoting Effects of Dietary Phytochemicals in Neurological Disorders. Molecular Nutrition and Food Research. 2019. 64(4):e1900550.
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2019 Oh, WY., Chiou, YS., Lee, PS., Pan, MH., Shahidi, F. Lipophilised resveratrol affects the generation of reactive nitrogen species in murine macrophages and cell viability of human cancer cell lines. Journal of Food Bioactives. 2019. 7:73–77.
2019 Koh, YC., Li, S., Chen, PY., Wu, JC., Kalyanam, N., Ho, CT., Pan, MH*. Prevention of Vascular Inflammation by Pterostilbene via Trimethylamine‐N‐Oxide Reduction and Mechanism of Microbiota Regulation. Molecular Nutrition and Food Research. 2019. e1900514.
2019 Chen, PY., Li, S., Koh, YC., Wu, JC., Yang, MJ., Ho, CT., Pan, MH*. Oolong Tea Extract and Citrus Peel Polymethoxyflavones Reduce Transformation of l-Carnitine to Trimethylamine-N-Oxide and Decrease Vascular Inflammation in l-Carnitine Feeding Mice. Journal of Agricultural and Food Chemistry. 2019. 67(28):7869-7879.
2019 Yang, G., Lin, CC., Yang, Y., Yuan, L., Wang, P., Wen, X., Pan, MH., Zhao, H., Ho, CT., Li, S. Nobiletin Prevents Trimethylamine Oxide-Induced Vascular Inflammation via Inhibition of the NF-κB/MAPK Pathways. Journal of Agricultural and Food Chemistry. 2019. 67(22):6169-6176.
2019 Hsiao, YH., Chen, NC., Koh, YC., Nagabhushanam, K., Ho, CT., Pan, MH*. Pterostilbene Inhibits Adipocyte Conditioned-Medium-Induced Colorectal Cancer Cell Migration through Targeting FABP5-Related Signaling Pathway. Journal of Agricultural and Food Chemistry. 2019. 10.1021/acs.jafc.9b03997.
2019 Lin, JN., Lee, PS., Mei, NW., Cheng, AC., Yu, RC., Pan, MH*. Effects of Ginseng Dietary Supplementation on a High-Fat Diet-induced obesity in C57BL/6 Mice. Food Science and Human Wellness. 2019. https://doi.org/10.1016/j.fshw.2019.03.003.
2019 Tung, YC., Chou, YC., Hung, WL., Cheng, AC., Yu, RC., Ho, CT., Pan, MH*. Polymethoxyflavones: Chemistry and Molecular Mechanisms for Cancer Prevention and Treatment. Current Pharmacology Reports. 2019. https://doi.org/10.1007/s40495-019-00170-z.
2019 Lin, IY., Chiou, YS., Wu, LC., Tsai, CY., Chen, CT., Chuang, WC., Lee, MC., Lin, CC., Lin, TT., Chen, SC., Pan, MH*, Ma, N*. CCM111 prevents hepatic fibrosis via cooperative inhibition of TGF-β, Wnt and STAT3 signaling pathways. Journal of Food and Drug Analysis. 2019. 27(1):184-194.
2019 Lien, KW., Ling, MP., Pan, MH*, Assessing Japan Imported Food Products Radiation Doses and Exposure Risk Following the Fukushima Nuclear Accident. Exposure and Health. 2019. https://doi.org/10.1007/s12403-019-00306-y.
2019 Lien, KW*, Chen, SY., Pan, MH, Ling, MP. Inspections of imported foods to Taiwan: an overview. Journal of Consumer Protection and Food Safety. 2019. https://doi.org/10.1007/s00003-018-1204-7.
2019 Lien, KW., Wang, X., Pan, MH, Ling, MP*. Assessing Aflatoxin Exposure Risk from Peanuts and Peanut Products Imported to Taiwan. Toxins. 2019. 11(2) 80.
2019 Wang, B*, Hui, Y., Liu, L., Zhao, A., Chiou, YS., Zhang, F., Pan, MH*. Optimized Extraction of Phenolics from Jujube Peel and Their Anti-inflammatory Effects in LPS-Stimulated Murine Macrophages. Journal of Agricultural and Food Chemistry. 2019. 67(6):1666-1673.
2019 Wang, S., Pan, MH., Hung, WL., Tung, YC., Ho, CT. From white to beige adipocytes: therapeutic potential of dietary molecules against obesity and their molecular mechanisms. Food & Function. 2019. doi: 10.1039/c8fo02154f.
2019 Lee, MJ*, Tsai, YJ., Lin, MY., You, HL., Kalyanam, N., Ho, CT., Pan, MH*. Calebin-A induced death of malignant peripheral nerve sheath tumor cells by activation of histone acetyltransferase. Phytomedicine. 2019. 3(57):377-384.
2019 Yi, X., Zheng, Q., Pan, MH., Chiou, YS, Li, Z., Li, L., Chen, Y., Hu, J., Duan, S., Wei, S., Ding, B*. Liposomal vesicles-protein interaction: Influences of iron liposomes on emulsifying properties of whey protein. Food Hydrocolloids. 2019. 89:602-612.
2019 Yi, X., Zheng, Q., Ding, B., Pan, MH., Chiou, YS, Li, L., Li, Z. Liposome-whey protein interactions and its relation to emulsifying properties. LWT - Food Science and Technology. 2019. 99 (2019):505-512.
2019 Lee, PS., Teng, CY., Kalyanam N., Ho, CT., Pan, MH*. Garcinol reduces obesity in high-fat diet-fed mice by modulating composition of the gut microbiota. Molecular Nutrition and Food Research. 2019. 63(2):e1800390.
2018 Pan, MH*., Chen, JW., Kong, ZL., Wu, JC., Ho, CT., Lai, CS. Attenuation by Tetrahydrocurcumin of Adiposity and Hepatic Steatosis in Mice with High-Fat-Diet-Induced Obesity. Journal of Agricultural and Food Chemistry. 2018. 66 (48), pp 12685–12695.
2018 Tung, YC., Chang, WT., Li, S., Wu, JC., Badmeav, V., Ho, CT., Pan, MH*. Citrus peel extracts attenuated obesity and modulated gut microbiota in mice with high-fat diet-induced obesity. Food & Function. 2018. 9; 3363-3373.
2018 Wang, X., Li, S., Wei, CC., Huang, J., Pan, MH., Shahidi, F., Ho, CT*. Anti-inflammatory effects of polymethoxyflavones from citrus peels: a review. Journal of Food Bioactives. 2018. 3:76-86.
2018 Chen, PY., Ho, CT., Shahidi, F., Pan, MH*. Potential effects of natural dietary compounds on trimethylamine N-oxide (TMAO) formation and TMAO-induced atherosclerosis. Journal of Food Bioactives. 2018. 3:87-94.
2018 Chiou, YS, Li, S, Ho, CT, Pan, MH*. Prevention of Breast Cancer by Natural Phytochemicals: Focusing on Molecular Targets and Combination Strategy. Molecular Nutrition & Food Research. 2018. doi: 10.1002/mnfr.201800392.
2018 Chou, YC, Ho, CT, Pan, MH*. Immature Citrus reticulate Extract Promotes Browning of Beige Adipocyte in High Fat Diet-Induced C57BL/6 Mice. Journal of Agricultural and Food Chemistry. 2018. doi: 10.1021/acs.jafc.8b02719.
2018 Bagal-Kestwal, DR, Pan, MH, Chiang, BH. Electrically nanowired-enzymes for probe modification and sensor fabrication. Biosensors and Bioelectronics. 2018. 121:223-235.
2018 Wang, L, Pan, MH, Lo, CY, Zhao, H, Li, S, Ho, CT, Yang, G. Anti-fibrotic activity of polyphenol-enriched sugarcane extract in rats via inhibition of p38 and JNK phosphorylation. Food & Function. 2018. 21;9(2):951-958. doi: 10.1039/c7fo01617d.
2018 Koh, YC, Pan, MH*. Review on Discovery and Development of Novel Phytochemicals Which can be Used in Functional Foods. Current Research in Nutrition and Food Science. 2018. 6(2).
2018 Koh, YC, Yang, GL, Lai, CS, Weerawatnanakorn, M, Pan, MH*. Chemopreventive Effects of Phytochemicals and Medicines on M1/M2 Polarized Macrophage Role in Inflammation-Related Diseases. International Journal of Molecular Science. 2018. 19(8):2208.
2018 Wu, JC, Tung, YC, Zheng, YN, Tsai, ML, Lai, CS, Ho, CT, Pan, MH*. 5-Demethylnobiletin is more effective than nobiletin in preventing AOM/DSS-induced colorectal carcinogenesis in ICR mice. Journal of Food Bioactives. 2018.
2018 Chiou, YS, Zheng, YN, Tsai, ML, Lai, CS, Ho, CT, Pan, MH*. 5-Demethylnobiletin more potently inhibits colon cancer cell growth than nobiletin in vitro and in vivo. Journal of Food Bioactives. 2018.
2018 Chiou, YS, Lee, PS, Pan, MH*. Food Bioactives and Their Effects on Obesity-Accelerated Inflammatory Bowel Disease. Journal of Agricultural and Food Chemistry. 2018. 31;66(4):773-779. doi: 10.1021/acs.jafc.7b05854.
2018 Chou, YC, Ho, CT, Pan, MH*. Stilbenes: Chemistry and Molecular Mechanisms of Anti-obesity. Current Pharmacology Reports. 2018.
2018 Pan, MH*, Wu, JC, Ho, CT, Lai, CS. Antiobesity molecular mechanisms of action: Resveratrol and pterostilbene. Biofactors. 2018. 44(1):50-60. doi: 10.1002/biof.1409.
2018 Lee, PS, Chiou, YS, Ho, CT, Pan, MH*. Chemoprevention by resveratrol and pterostilbene: Targeting on epigenetic regulation. Biofactors. 2018. 44(1):26-35. doi: 10.1002/biof.1401.
2018 Wu, JC, Tsai, ML, Lai, CS, Lo, CY, Ho, CT, Wang, YJ, Pan, MH*. Polymethoxyflavones precent benzo[a]pyrene/dextran sodium sulfate-induced colorectal carcinogenesis through modulating xenobiotic metabolism and ameliorate autophagic defect in ICR mice. International Journal of Cancer. 2018. 15; 142(8):1689-1701
2017 Hung, WL, Yang, G, Wang, YC, Chiou, YS, Tung, YC, Yang MJ, Wang, BN, Ho, CT, Wang, Y, Pan, MH*. Protective effects of theasinensin A against carbon tetrachloride-induced liver injury in mice. Food & Function. 2017. 8(9):3276-3287.
2017 Kimura, S, Tung, YC, Pan, MH, Su, NW, Lai, YJ, Cheng, KC. Black garlic: A critical review of its production, bioactivity, and application. Journal of Food and Drug Analysis. 2017. 25(1):62-70.
2017 Tung, YC, Hsieh, PH, Pan, MH*, Ho, CT. Cellular models for the evaluation of the anti-obesity effect of selected phytochemicals from food and herbs. Journal of Food and Drug Analysis. 2017. 25(1): 100-110.
2017 Wu, JC, Lai, CS, Tsai, ML, Ho, CT, Wang, YJ, Pan, MH*. Chemopreventive effect of natural dietary compounds on xenobiotic-induced toxicity. 2017. 25(1): 176-186.
2017 Weerawatanakorn, M, Pan, MH. Phytochemical components of Carissa carandas and the inhibitory effects of fruit juice on inducible nitric oxide synthase and cyclooxygenase-2. Journal of Food Biochemistry. 2017. 41(3): e12343.
2017 Lin, IY, Pan, MH, Lai, CS, Lin, TT, Chen, CT, Chung, TS, Chen, CL, Lin, CH, Chuang, WC, Lee, MC, Lin, CC, Ma, N. CCM111, the water extract of Antrodia cinnamomea, regulates immune-related activity through STAT3 and NF-κB pathways. Scientific Reports. 2017. 7(1):4862.
2017 Lee, PS, Lee, CH, Pan, MH*. Cancer chemoprevetive effects of phytochemicals by suppressing cancer metastasis. Journal of Analytical & Pharmaceutical Research. 2017. 5(6): 00157.
2017 Chen, RJ, Wu, PH, Ho, CT, Way, TD, Pan, MH, Chen, HM, Ho, YS, Wang, YJ. P53-dependent downregulation of hTERT protein expression and telomerase activity induces senescence in lung cancer cells as a result of pterostilbene treatment. Cell Death and Disease. 2017. 8(8):e2985.
2017 Pan, MH*, Yang, G, Li, S, Li, MY, Tsai, ML, Wu, JC, Badmaev, V, Ho, CT, Lai, CS. Combination of citrus polymethoxyflavones, green tea polyphenols and Lychee extracts suppresses obesity and hepatic steatosis in high-fat diet induced obese mice. Molecular Nutrition & Food Research. 2017. 61(11).
2017 Pan, MH*, Wu, JC, Ho, CT, Badmaev, V. Effects of water extract of Curcuma longa (L.) roots on immunity and telomerase function. Journal of Complementary and Integrative Medicine. 2017. doi: 10.1515/jcim-2015-0107.
2017 Chou, YC, Suh, JH, Wang, Y, Pahwa, M, Badmaev, V, Ho, CT, Pan, MH*. Boswellia serrata resin extract alleviates azoxymethane (AOM)/dextran sodium sulfate (DSS)-induced colon tumorigenesis. Molecular Nutrition & Food Research. 2017. 61(9).
2017 Pan, MH*. Introduction to the Special Issue: Dietary Natural Compounds. Journal of Food and Drug Analysis. 2017. 25(1): 1–2.
2017 Chen, HP, Pan, MH, Chou, YY, Sung, C, Lee, KH, Leung, CM, Hsu, PC. Effects of di(2-ethylhexyl)phthalate exposure on 1,2-dimethyhydrazine-induced colon tumor promotion in rats. Food and Chemical Toxicology. 2017. 103: 157–167.
2017 Tu, SH, Chiou, YS, Kalyanam, N, Ho, CT, Chen, LC, Pan, MH*. Garcinol sensitizes breast cancer cells to Taxol through the suppression of caspase-3/iPLA2 and NF-κB/Twist1 signaling pathways in a mouse 4T1 breast tumor model. Food & Function. 2017. 22;8(3):1067-1079.
2017 Tang, W. Li, S, Liu, Y, Wu, JC, Pan, MH, Huang, MT, Ho, CT. Anti-diabetic activities of cis- and trans-2,3,5,4'-tetrahydroxystilbene 2-O-β-glucopyranoside from Polygonum multiflorum. Molecular Nutrition & Food Research. 2017. doi: 10.1002/mnfr.201600871.
2017 Yang, GL, Li, Shiming, Yuan, Li, Yang, Yiwen, Pan, MH*. Effect of nobiletin on the MAPK/NF-κB signaling pathway in the synovial membrane of rats with arthritis induced by collagen. Food and Function. 2017. doi: 10.1039/c7fo01311f
2017 Wang, SY, Wang, Y, Pan, MH , Ho, CT. Anti-obesity molecular mechanism of soy isoflavones: weaving the way to new therapeutic routes. Food and Function. 2017. doi: 10.1039/c7fo01094j
2017 Lai, CS, Yang, GL, Li, SM, Lee, PS, Wang, BN, Chung, MC, Nagabhushanam, K, Ho, CT, Pan, MH*. 3’-Hydroxypterostilbene suppresses colitis-associated tumorigenesis by inhibition of IL-6/STAT3 signaling in mice. Journal of Agricultural and Food Chemistry. 2017. 65(44):9655-9664.
2016 Lai, CS, Wu, JC, Ho, CT, Pan, MH*. Chemoprevention of obesity by dietary natural compounds targeting mitochondrial regulation. Molecular Nutrition & Food Research. 2016. 61(6). doi: 10.1002.
2016 Pan, MH*, Tung, YC*, Yang, G, Li, S, Ho, CT. Molecular mechanisms of the anti-obesity effect of bioactive compounds in tea and coffee. Food & Function. 2016. 7(11): 4481-4491.
2016 Tung, YC, Lin, YH, Chen, HJ, Chou, SC, Cheng, AC, Kalyanam, N, Ho, CT, Pan, MH*. Piceatannol exerts anti-obesity effects in C57BL/6 mice through modulating adipogenic proteins and gut microbiota. Molecules. 2016. 21(11): 1419.
2016 Liou, WS, Lin, C, Lee, PS, Kalyanam, N, Ho, CT, Pan, MH*. Calebin-A induces cell cycle arrest in human colon cancer cells and xenografts in nude mice. Journal of Functional Foods. 2016. 26:781-791.
2016 Chiou, YS, John, JA, Ho, CT, Pan, MH*, Shahidi, FS. Evaluation of chemopreventive effects in colitis-associated colon tumourigenesis and oral toxicity of the lipophilic epigallocatechin gallate-docosahexaenoic acid. Journal of Functional Foods. 2016. 24:48-56.
2016 Wu, JC, Lai, CS, Lee, PS, Ho, CT, Liou, WS, Wang, YJ, Pan, MH*. Anti-cancer efficacy of dietary polyphenols is mediated through epigenetic modifications. Current Opinion in Food Science. 2016. 8:1-7.
2016 Hung, WL, Hwang, LS, Shahidi, F, Pan, MH, Wang, Y, Ho, CT. Endogenous formation of trans fatty acids: Health implications and potential dietary intervention. Journal of Functional Foods. 2016. 25:14-24.
2016 Wang, Y, Lee, PS, Chen, YF, Ho, CT and Pan, MH*. Suppression of Adipogenesis by 5-Hydroxy-3,6,7,8,3’,4’-Hexamethoxyflavone from Orange Peel in 3T3-L1 Cells. Journal of Medicinal Food. 2016. 19(9): 830-835.
2016 Tsai, JH, Hsu, LS, Huang, HC, Lin, CL, Pan, MH, Hong HM and Chen WJ. 1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione induces G1 cell cycle arrest and autophagy in hela cervical cancer cells. International Journal of Molecular Sciences. 2016. 17(8):1274.
2016 Chena, LC, Chen, MY, Tu, SH, Pan, MH, Lo, CY, Ho, CT, Wu, CH, Ho, YS. Pu-erh tea attenuates smoking-induced foam cell formation through inhibition of the α9-nicotinic-acetylcholine receptor expression in monocytes: An ex vivo study. Journal of Functional Foods. 2016. 22:132-144.
2016 Lai, CS, Chen YY, Lee, PS, Kalyanam, N, Ho, CT, Liou, WS, Yu, RC, Pan, MH*. Bisdemethoxycurcumin Inhibits Adipogenesis in 3T3-L1 Preadipocytes and Suppresses Obesity in High-Fat Diet-Fed C57BL/6 Mice. Journal of Agricultural and Food Chemistry. 2016. 64 (4):821-830.
2016 Zhen, J, Villani, TS, Guo, Y, Qi, Y, Chin, K, Pan, MH, Ho, CT, Simon, JE, Wu, Q. Phytochemistry, antioxidant capacity, total phenolic content and anti-inflammatory activity of Hibiscus sabdariffa leaves. Food Chemistry. 2016. 190:673-680.
2016 Chiou, YS.; Huang, Q, Ho, CT, Wang, YJ, Pan, MH*. Directly interact with Keap1 and LPS is involved in the anti-inflammatory mechanisms of (-)-epicatechin-3-gallate in LPS-induced macrophages and endotoxemia. Free Radical Biology and Medicine. 2016. 94:1-16.
2016 Chen, W, Jia, Z, Pan, MH, Babu, PV. A. Natural Products for the Prevention of Oxidative Stress-Related Diseases: Mechanisms and Strategies. Oxidative Medicine and Cellular Longevity. 2016.
2016 Tu, SH.; Chen, MY, Chen, LC, Mao, YT, Ho, CH, Lee, WJ, Lin, YK, Pan, MH, Lo, CY, Chen, CL. Pu-erh Tea Extract Attenuates Nicotine-Induced Foam Cell Formation in Primary Cultured Monocytes: An in Vitro Mechanistic Study. Journal of Agricultural and Food Chemistry. 2016. 64 (16):3186-3195.
2016 Tung, YC.; Li, S, Huang, Q, Hung, WL, Ho, CT, Wei, GJ, Pan, MH*. 5-Demethylnobiletin and 5-Acetoxy-6, 7, 8, 3’, 4’-pentamethoxyflavone Suppress Lipid Accumulation by Activating the LKB1-AMPK Pathway in 3T3-L1 Preadipocytes and High Fat Diet-Fed C57BL/6 Mice. Journal of Agricultural and Food Chemistry. 2016. 64 (16):3196-3205.
2016 Pan, MH, Maresz, K, Lee, PS, Wu, JC, Ho, CT, Popko, J, Mehta, DS, Stohs, SJ, Badmaev, V. Inhibition of TNF-α, IL-1α, and IL-1β by Pretreatment of Human Monocyte-Derived Macrophages with Menaquinone-7 and Cell Activation with TLR Agonists In Vitro. Journal of Medicinal Food. 2016. 19(7):663-669.
2015 Lai, CS., Liao, SN, Tsai, ML, Kalyanam, N, Majeed, M, Majeed, A, Ho, CT, Pan, MH.* Calebin-A inhibits adipogenesis and hepatic steatosis in high-fat diet-induced obesity via activation of AMPK signaling. Molecular Nutrition and Food Research. 2015. 59(10):1883-1895.
2015 Wang, Y, Tsai, ML, Chiou, LY, Ho, CT, Pan, MH*. Antitumor Activity of Garcinol in Human Prostate Cancer Cells and Xenograft Mice. Journal of Agricultural and Food Chemistry. 2015. 63(41):9047-9052.
2015 Hung, WL, Liu, CM, Lai, CS, Ho, CT, Pan, MH*. Inhibitory effect of garcinol against 12-O-tetradecanoylphorbol 13-acetate-induced skin inflammation and tumorigenesis in mice. Journal of Functional Foods. 2015. 18:432-444.
2015 Weerawatanakorn, M, Wu, JC, Pan, MH. Ho CT. Reactivity and stability of selected flavor compounds. Journal of Food and Drug Analysis , 2015. 23(2):176-190.
2015 Ting, YW, Chiou, YS, Jiang, Y, Pan, MH, Lin, Z, Huang, Q. Safety evaluation of tangeretin and the effect of using emulsion-based delivery system: Oral acute and 28-day sub-acute toxicity study using mice. Food Research International. 2015. 74:140-150.
2015 Tung, YC, Tsai, ML, Kuo, FL, Lai, CS, Badmaev, V, Ho, CT, Pan, MH*. Se-Methyl-L-selenocysteine Induces Apoptosis via Endoplasmic Reticulum Stress and the Death Receptor Pathway in Human Colon Adenocarcinoma COLO 205 Cells. Journal of Agricultural and Food Chemistry. 2015. 63(20):5008-5016.
2015 Weerawatanakorn, M, Lee, YL, Tsai, CY, Lai, CS, Wan, X, Ho, CT, Li, S, Pan, MH*. Protective effect of theaflavin-enriched black tea extracts against dimethylnitrosamine-induced liver fibrosis in rats. Food & Function. 2015. 6: 1832-1840.
2015 Bai N, He K, Roller M, Lai CS, Bai L, Pan, MH*. Flavonolignans and other constituents from Lepidium meyenii with activities in anti-inflammation and human cancer cell lines. Journal of Agricultural and Food Chemistry. 2015. 63(9):2458-2463.
2015 Hsu, PC, Kuo, YT, Leon, Guo Y, Chen, JR, Tsai, SS, Chao, HR, Teng, YN, Pan, MH*. The adverse effects of low-dose exposure to Di(2-ethylhexyl) phthalate during adolescence on sperm function in adult rats. Environmental Toxicology. 2014. 31(6):706-712.
2015 Pan, MH*, Chiou, YS, Chen, LH, Ho, CT. Breast cancer chemoprevention by dietary natural phenolic compounds: specific epigenetic related molecular targets. Molecular Nutrition and Food Research. 2015. 59(1):21-35.
2015 Huang, CY, Hsieh, NT, Pan, MH, Li, CI, Chou, YH, Chiou, YS, Lee MF. Resveratrol and pterostilbene regulate MED28 (magicin/EG1) expression and cell growth in MCF7 human breast cancer cells. Journal of Functional Foods. 2015. 12:158–167.
2015 Ting, Y, Chiou, YS, Pan, MH, Ho, CT, Huang, Q. In vitro and in vivo anti-cancer activity of tangeretin against colorectal cancer was enhanced by emulsion-based delivery system. Journal of Functional Foods. 2015. 15:267-273.
2015 Badmaev, V, Hatakeyama, Y, Yamazaki, N, Noro, A, Mohamed, F, Ho, CT, Pan, MH*. Preclinical and clinical effects of Coleus forskohlii, Salacia reticulata and Sesamum indicum modifying pancreatic lipase inhibition in vitro and reducing total body fat. Journal of Functional Foods. 2015. 15:44-51.
2015 Ravishankar, B, Dound, YA, Mehta, DS, Ashok, BK, Souza, A, Pan, MH*, Ho CT, Badmaev V, Vaidya ADB. Safety assessment of menaquinone-7 for use in human nutrition. Journal of Food and Drug Analysis. 2015. 23:99-108.
2015 Lai, CS, Wu, JC, Pan, MH*. Molecular mechanism on functional food bioactives for anti-obesity. Current Opinion in Food Science. 2015. 2:9-13.
2015 Lee MF, Lai CS, Cheng AC, Hou JS, Badmaevd V, Ho CT, Pan MH*. Krill oil and xanthigen separately inhibit high fat diet induced obesity and hepatic triacylglycerol accumulation in mice. Journal of Functional Foods. 2015. 19:913-921.
2015 Janporna S, Ho CT, Chavasitc V, Pan MH, Chittrakorna S, Ruttarattanamongkola K, Weerawatanakorn M. Physicochemical properties of Terminalia catappa seed oil as a novel dietary lipid source. Journal of Food and Drug Analysis, 2015. 23(2):201-209.
2015  
2014 Cheng TC, Lai CS, Chung MC, Kalyanam N, Majeed M, Ho CT, Ho YS, Pan MH*. Potent Anti-Cancer Effect of 3'-Hydroxypterostilbene in Human Colon Xenograft Tumors. PLoS One. 2014. 9(11):1-8.
2014 Hung WL, Tsai ML, Sun PP, Tsai CY, Yang CC, Ho CT, Cheng AC, Pan MH*. Protective effects of garcinol on dimethylnitrosamine-induced liver fibrosis in rats. Food & Function. 2014. 5:2883–2891.
2014 Ma N, Lai CS, Chung CH, Yang JM, Hsu KC, Chen CY, Chung TS, Li S, Ho CT, Pan MH*. 5-Demethyltangeretin is more potent than tangeretin in inhibiting dimethylbenz(a)anthracene (DMBA)/12-O-tetradecanoylphorbol-13-acetate (TPA)-induced skin tumorigenesis. Journal of Functional Foods. 2014. 11:528-537.
2014 Tsai ML, Chiou YS, Chiou LY, Ho CT, Pan MH*. Garcinol suppresses inflammation -associated colon carcinogenesis in mice. Molecular Nutrition and Food Research. 2014. 58(9):1820-1829.
2014 Chiou YS, Wu JC, Huang Q, Shahidi F, Wang Y J, Ho CT, Pan MH*. Metabolic and colonic microbiota transformation may enhance the bioactivities of dietary polyphenols. Journal of Functional Foods. 2014 7:3-25.
2014 Weerawatanakorn M, Hsieh SC, Tsai ML, Lai CS,Wu LM, Badmaev V, Ho CT, Pan MH*. Inhibitory effect of tetrahydrocurcumin on dimethylnitrosamine-induced liver fibrosis in rats. Journal of Functional Foods. 2014. 7:305-313.
2014 Weerawatanakorn M, Yang JR, Tsai ML, Lai CS, Ho CT, Pan MH*. Inhibitory effects of Momordica grosvenori Swingle extracts on 12-Otetradecanoylphorbol-13-acetate-induced skin inflammation and tumor promotion in mouse skin. Food & Function. 2014. 5(2):257-264.
2014 Pan MH*, Lai CS, Tsai ML, Ho CT. Chemoprevention of nonalcoholic fatty liver disease by dietary natural compounds. Molecular Nutrition and Food Research. 2014. 58(1):147-171.
2014 Wu JC, Tsai ML, Lai CS, Wang YJ, Ho CT, Pan MH*. Chemopreventative effects of tetrahydrocurcumin on human diseases. Food & Function. 2014. 5(1):12-17.
2014 Chu HF, Pan MH, Ho CT, Tseng YH, Wang WW, Chau CF. Variations in the Efficacy of Resistant Maltodextrin on Body Fat Reduction in Rats Fed Different High-Fat Models. Journal of Agricultural and Food Chemistry, 2014. 62(1),192-197.
2013 Wang CH, Lin JH, Lu TJ, Chiang AN, Chiou ST, Chen YA, Pan MH, Hsieh SC. Establishment of reporter platforms capable of detecting NFkappaB mediated immuno-modulatory activity. Journal of Agricultural and Food Chemistry. 2013. 1(51):12582-12587.
2013 Hsu CH, Ho YS, Lai CS, Hsieh SC, Chen LH, Lin E, Ho CT, Pan MH*. Hexahydro-b-acids potently inhibit 12-O-tetradecanoylphorbol 13-acetateinduced skin inflammation and tumor promotion in mice. Journal of Agricultural and Food Chemistry. 2013. 61(47):11541-11549.
2013 Tsai JH, Hsu LS, Lin CL, Hong HM, Pan MH, Way TD, Chen WJ. 3,5,4'-Trimethoxystilbene, a natural methoxylated analog of resveratrol, inhibits breast cancer cell invasiveness by downregulation of PI3K/Akt and Wnt/b-catenin signaling cascades and reversal of epithelial-mesenchymal transition. Toxicology and Applied Pharmacology. 2013. 272(3):746-756.
2013 Coppin J, Xu Y, Chen H, Pan MH, Ho CT, Juliani R, Simon JE, Wu Q. Determination of flavonoids by LC/MS and anti-inflammatory activity in Moringa oleifera. Journal of Functional Foods. 2013. 5 (4):1892-1899.
2013 Lai CS, Ho MH, Tsai ML, Li S, Badmaev V, Ho CT, Pan MH*. Suppression of adipogenesis and obesity in high-fat induced mouse model by hydroxylated polymethoxyflavones. Journal of Agricultural and Food Chemistry. 2013. 61(43):10320-10328.
2013 Ting Y, Li CC, Pan MH, Ho CT, Huang Q. Effect of a labile methyl donor on the transformation of 5-demethyltangeretin and the related implication on bioactivity. Journal of Agricultural and Food Chemistry. 2013. 61(34):8090-8097.
2013 Tseng LH, Hsu PC, Lee CW, Tsai SS, Pan MH, Li MH. Developmental exposure to decabrominated diphenyl ether (BDE-209): effects on sperm oxidative stress and chromatin DNA damage in mouse offspring. Environmental Toxicology. 2013. 28(7):380-389.
2013 Chiou YS, Sang S, Cheng KH, Ho CT, Wang YJ, Pan MH*. Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently prevents skin carcinogenesis by suppressing the PKD1- dependent signaling pathway in CD34+ skin stem cells and skin tumors . Carcinogenesis. 2013. 34(6):1315-1322.
2013 Lai CS, Li S, Miyauchi Y, Suzawa M, Ho CT, Pan MH*. Potent anticancer effects of citrus peel flavonoids in human prostate xenograft tumors. Food & Function. 2013. 4(6):944-9.
2013 Lee MF, Liu ML, Cheng AC, Tsai ML, Ho CT, Liou WS, Pan MH*. Pterostilbene inhibits dimethylnitrosamine-induced liver fibrosis in rats . Food Chemistry. 2013. 138(2-3):802-807.
2013 Huang CS, Ho CT, Tu SH, Pan MH, Chuang CH, Chang HW, Chang CH, Wu CH, Ho YS. Long-term ethanol exposure-induced hepatocellular carcinoma cell migration and invasion through lysyl oxidase activation are attenuated by combined treatment with pterostilbene and curcumin analogues. Journal of Agricultural and Food Chemistry. 2013. 61(18):4326-4335.
2013 Lai CS, Li S, Liu CB, Miyauchi Y, Suzawa M, Ho CT, Pan MH*. Effective suppression of azoxymethane-induced aberrant crypt foci formation in mice with citrus peel flavonoids. Molecular Nutrition and Food Research. 2013. 57(3):551-555.
2013 Pan MH*, Lai CS, Wang H, Lo CY, Ho CT, Li S. Black tea in chemoprevention of cancer and other human diseases. Food Science and Human Wellness. 2013. 2(1):12-21.
2013 Lee MF, Tsai ML, Sun PP, Chien LL, Cheng AC, Ma NJ, Ho CT, Pan MH*. Phyto-power dietary supplement potently inhibits dimethylnitrosamine induced liver fibrosis in rats. Food & Function. 2013. 4(3):470-475.
2013 Li S, Lo CY, Pan MH, Lai CS, Ho CT. Black tea: chemical analysis and stability. Food & Function. 2013. 4(1):10-18.
2013 Pan MH*, Lai CS, Wu JC, Ho CT. Epigenetic and disease targets by polyphenols. Current Pharmaceutical Design. 2013. 19(34):6156-6185.
2012 Pan MH*, Li S, Lai CS, Miyauchi Y, Suzawa M, Ho CT. Inhibitory effect of citrus flavonoids on 12-O-tetradecanoylphorbol 13-acetate-induced skin inflammation and tumor promotion in mice. Food Science and Human Wellness. 2012. 1(1):65-73.
2012 Chen RJ, Tsai SJ, Ho CT, Pan MH, Ho YS, Wu CH, Wang YJ. Chemopreventive effects of pterostilbene on urethane-induced lung carcinogenesis in mice via the inhibition of EGFR-mediated pathways and the induction of apoptosis and autophagy. Journal of Agricultural and Food Chemistry. 2012. 60(46):11533-11541.
2012 Tsai ML, Lai CS, Chang YH, Chen WJ, Ho CT, Pan MH*. Pterostilbene, a natural analogue of resveratrol, potently inhibits 7,12-dimethylbenz[a]anthracene (DMBA)/ 12-O-tetradecanoylphorbol -13-acetate (TPA)-induced mouse skin carcinogenesis. Food & Function. 2012. 3(11):1185-1194.
2012 Chang LH, Huang HS, Wu PT, Jou IM, Pan MH, Chang WC, Wang DD, Wang JM. Role of Macrophage CCAAT/Enhancer Binding Protein Delta in the Pathogenesis of Rheumatoid Arthritis in Collagen-Induced Arthritic Mice. PLoS One. 2012. 7(9):1-14.
2012 Zhong Y, Chiou YS, Pan MH, Shahidi F. Anti- inflammatory activity of lipophilic epigallocatechin gallate (EGCG) derivatives in LPS-stimulated murine macrophages. Food Chemistry. 2012. 134(2):742-748.
2012 Kuo YC, Lai CS, Tsai CY, Nagabhushanam K, Ho CT, Pan MH*. Inotilone suppresses phorbol ester–induced inflammation and tumor promotion in mouse skin. Molecular Nutrition and Food Research. 2012. 56(8):1324-1332.
2012 Lin VC, Tsai YC, Lin JN, Fan LL, Pan MH, Ho CT, Wu JY, Way TD. Activation of AMPK by pterostilbene suppresses lipogenesis and cell cycleprogression in p53 positive and negative human prostate cancer cells. Journal of Agricultural and Food Chemistry. 2012. 60(25):6399-6407.
2012 Chiou YS, Ma NJ, Sang S, Ho CT, Wang YJ, Pan MH*. Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently suppresses dextran sulfate sodium-induced colitis and colon tumorigenesis in mice. Journal of Agricultural and Food Chemistry. 2012. 60(13):3441-3451.
2012 Lai CS, Tsai ML, Badmaev V, Jimenez M, Ho CT, Pan MH*. Xanthigen suppresses preadipocyte differentiation and adipogenesis through down-regulation of PPARr and C/EBPs, and modulation of SIRT-1, AMPK and FOXO pathways. Journal of Agricultural and Food Chemistry. 2012. 60(4):1094-1101.
2012 Ou JL, Tu CC, Hsu PI, Pan MH, Lee CC, Tsay FW, Wang HM, Cheng LC, Lai KH, Yu HC. Prevalence and risk factors of erosive esophagitis in Taiwan. Journal of the Chinese Medical Association. 2012. 75(2):60-64.
2012 Hsieh WJ, Chiou ST, Pan MH, Hsieh SC. Establishment and Evaluation of Biotechnological Platform for Screening Health Food with Antiinflammation Ability. Journal of Traditional and Complementary Medicine. 2012. 2(1):76-80.
2012 Pan MH*, Lai CS, Tsai ML, Wu JC, Ho CT. Molecular mechanisms for anti-aging by natural dietary compounds. Molecular Nutrition and Food Research. 2012. 56(1):88-115.
2012 Zhong Y, Chiou YS, Pan MH, Ho CT, Shahidi F. Protective effects of epigallocatechin gallate (EGCG) derivatives on azoxymethane-induced colonic carcinogenesis in mice. Journal of Functional Foods. 2012. 4(1):323-330.
2012 Ho, CT, Pan MH, Lai, CS, Li, S. Polymethoxyflavones as food factors for the management of inflammatory diseases. Journal of Food and Drug Analysis. 2012. 20:337-341.
2012 Kuo, JM, Yang, JI, Chen, WM, MH Pan, Tsai, ML, Lai YJ, Hwang, A, Pan BS, Lin CY. Purification and characterization of a thermostable keratinase from Meiothermus sp. I40. International Biodeterioration and Biodegradation. 2012. 70:111-116.
2011 Lai, CS, Wu, JC, Yu, SF, Badmaev, V, Nagabhushanam, K, Ho, CT, Pan MH*. Tetrahydrocurcumin is more effective than curcumin in preventing azoxymethane-induced colon carcinogenesis. Molecular Nutrition and Food Research. 2011. 55(12):1819-1828.
2011 Lai CS, Pan MH. Mechanism for Possible Chemopreventive Effects of Natural Dietary Compounds on Smoking-induced Tumorigenesis. Journal of Experimental & Clinical Medicine. 2011. 3(6):262-271.
2011 Wu, JC, Lai, CS, Badmaev, V, Nagabhushanam, K, Ho, CT, Pan MH*. Tetrahydrocurcumin, a major metabolite of curcumin, induced autophagic cell death through coordinative modulation of PI3K/Akt-mTOR and MAPK signaling pathways in human leukemia HL-60 cells. Molecular Nutrition and Food Research. 2011. 55(11):1646-1654.
2011 Pan MH*, Chiou, YS, Tsai ML, Ho CT. Anti-inflammatory activity of traditional Chinese medicinal herbs. Journal of Traditional and Complementary Medicine. 2011. 1(1):8-24.
2011 Qiu P, Guan H, Dong P, Guo S, Zheng J, Li S, Chen Y, Ho CT, Pan MH, McClements DJ, Xiao H. The inhibitory effects of 5-hydroxy- 3,6,7,8,3',4'-hexamethoxyflavone on human colon cancer cells. Molecular Nutrition and Food Research. 2011. 55(10):1523-1532.
2011 Shen D, Pan MH, Wu QL, Park CH, Juliani HR, Ho CT, Simon JE. A Rapid LC/MS/MS Method for the Analysis of Nonvolatile Antiinflammatory Agents from Mentha spp. Journal of Food Science. 2011. 76(6):900-908.
2011 Kuo DH, Tsai SW, Pan MH*. Magnolol blocks homocysteine-induced endothelial dysfunction in porcine coronary arteries. Food Chemistry. 2011. 127:135- 140.
2011 Lai CS, Lai YS, Kuo DH, Wu CH, Ho CT, Pan MH*. Magnolol potently suppressed lipopolysaccharide-induced iNOS and COX-2 expression via downregulating MAPK and NF-kB signaling pathways. Journal of Functional Foods. 2011. 3(3):198-206.
2011 Kong ZL, Yu SC, Dai SA, Tu CC, Pan MH, Liu YC. Polyoxygenated Sterols from Freshwater Clam. Helvetica Chimica Acta, 2011, 94(5):892-896.
2011 Pan MH*, Hong HM, Lin CL, Jhang AZ, Tsai JH, Badmaev V, Nagabhushanam K, Ho CT, Chen WJ. Se-methylselenocysteine inhibits lipopolysaccharide-induced NF-κB activation and iNOS induction in RAW 264.7 murine macrophages. Molecular Nutrition and Food Research. 2011. 55(5):723-32.
2011 Tang W, Chen LH, Daun H, Ho CT, Pan MH*. Inhibitory effects of hexahydro-bata-acids in LPS-stimulated murine macrophage. Journal of Functional Foods. 2011. 3:215-222.
2011 Yen JH, Weng CY, Li S, Lo YH, Pan MH, Fu SH, Ho CT, Wu MJ. Citrus flavonoid, 5-demethylnobiletin, suppresses scavenger receptor expression in THP-1 cells and alters lipid homeostasis in HepG2 liver cells. Molecular Nutrition and Food Research. 2011. 55(5):733-748.
2011 Liu CB, Chen LH, Cheng AC, Chen WJ, Tsai ML, Liu Y, Ho CT, Pan MH*. Hexahydro-b-acids induce apoptosis through mitochondrial pathway, GADD153 expression, and caspase activation in human leukemia cells. Food and Chemical Toxicology. 2011. 49(4):1033-1042.
2011 Qiu P, Guan H, Dong P, Li S, Ho CT, Pan MH, McClements DJ, Xiao H. The p53, Bax, and p21-dependent inhibition of colon cancer cell growth by 5-hydroxy polymethoxyflavones. Molecular Nutrition and Food Research. 2011. 55(4):613-622.
2011 Bai N, He K, Roller M, Lai CS, Shao X, Pan MH, Bily A, Ho CT. Flavonoid glycosides from Microtea debilis and their cytotoxic and anti-inflammatory effects. Fitoterapia. 2011. 82(2):168-172.
2011 Tu SH, Ku CY, Ho CT, Chen CS, Huang CS, Lee CH, Chen LC, Pan MH, Chang HW, Chang CH, Chang YJ, Wei PL, Wu CH, Ho YS. Tea polyphenol (-)-epigallocatechin-3-gallate inhibits nicotine- and estrogen-induced a9-nicotinic acetylcholine receptor upregulation in human breast cancer cells. Molecular Nutrition and Food Research. 2011. 55(3):455-466.
2011 Cheng AC, Lee MF, Tsai ML, Lai CS, Lee JH, Ho CT, Pan MH*. Rosmanol potently induces apoptosis through both the mitochondrial apoptotic pathway and death receptor pathway in human colon adenocarcinoma COLO 205 cells. Food and Chemical Toxicology. 2011. 49(2):485-493.
2011 Chiou YS, Tsai ML, Nagabhushanam K, Wang YJ, Wu CH, Ho CT, Pan MH*. Pterostilbene is more potent than resveratrol in preventing azoxymethane (AOM)-induced colon tumorigenesis via activation of the NF-E2- related factor 2 (Nrf2)-mediated antioxidant signaling pathway. Journal of Agricultural and Food Chemistry. 2011. 59(6):2725-2733.
2011 Lai CS, Tsai ML, Cheng AC, Li S, Lo CY, Wang Y, Xiao H, Ho CT, Wang YJ, Pan MH*. Chemoprevention of colonic tumorigenesis by dietary hydroxylated polymethoxyflavones in azoxymethane-treated mice. Molecular Nutrition and Food Research. 2011. 55(2):278-290.
2011 Pan MH*, Chiou YS, Wang YJ, Ho CT, Lin JK. Multistage carcinogenesis process as molecular targets in cancer chemoprevention by epicatechin-3-gallate. Food & Function. 2011. 2(2):101-110.
2011 Pan MH*, Lin YT, Lin CL, Wei CS, Ho CT, Chen WJ. Suppression of Heregulin-β1/HER2-Modulated Invasive and Aggressive Phenotype of Breast Carcinoma by Pterostilbene via Inhibition of Matrix Metalloproteinase-9, p38 Kinase Cascade and Akt Activation. Evidence-Based Complementary and Alternative Medicine. 2011. 2011:1-12.
2011 Chen CS, Lee CH, Hsieh CD, Ho CT, Pan MH, Huang CS, Tu SH, Wang YJ, Chen LC, Chang YJ, Wei PL, Yang YY, Wu CH, Ho YS. Nicotineinduced human breast cancer cell proliferation attenuated by garcinol through down-regulation of the nicotinic receptor and cyclin D3 proteins. Breast Cancer Research and Treatment. 2011. 125(1):73-87.
2011 Pan MH*, Lai CS, Wu JC, Ho CT. Molecular mechanisms for chemoprevention of colorectal cancer by natural dietary compounds. Molecular Nutrition and Food Research. 2011. 55(1):32-45.
2011 Lee MF, Pan MH, Chiou YS, Cheng AC, Huang H. Resveratrol modulates MED28 (magicin/EG-1) expression and inhibits epidermal growth factor (EGF)-induced migration in MDA-MB-231 human breast cancer cells. Journal of Agricultural and Food Chemistry. 2011. 59(21):11853-11861.
2010 Cheng AC, Tsai ML, Liu CM, Lee MF, Nagabhushanam K, Ho CT, Pan MH*. Garcinol inhibits cell growth in hepatocellular carcinoma Hep3B cells through induction of ROS-dependent apoptosis. Food & Function. 2010. 1(3):301-307.
2010 Kuo DH, Kang WH, Shieh PC, Chen FA, Chang CD, Tsai ML, Ho CT, Pan MH*. Protective effect of Pracparatum mungo extract on carbon tetrachloride-induced hepatotoxicity in rats. Food Chemistry. 2010. 123(4): 1007-1012.
2010 Pan MH, Tsai ML, Chen WM, Hwang A, Sun Pan B, Hwang YR, Kuo JM. Purification and Characterization of a Fish Scale-Degrading Enzyme from a Newly Identified Vogesella sp. Journal of Agricultural and Food Chemistry. 2010. 58(23):12541–12546.
2010 Pan YC, Li CF, Ko CY, Pan MH, Chen PJ, Tseng JT, Wu WC, Chang WC, Huang AM, Sterneck E, Wang JM. CEBPD reverses RB/E2F1- mediated gene repression and participates in HMDB-induced apoptosis of cancer cells. Clinical Cancer Research. 2010. 16(23):5770-5780.
2010 Bai N, He K, Zhou Z, Lai CS, Zhang L, Quan Z, Shao X, Pan MH, Ho CT. Flavonoids from Rabdosia rubescens exert anti-inflammatory and growth inhibitory effect against human leukemia HL-60 cells. Food Chemistry. 2010. 122(3):831-835.
2010 Pan MH*, Lai CS, Ho CT. Anti-inflammatory activity of natural dietary flavonoids. Food & Function. 2011. 1(1):15-31.
2010 Wang BJ, Sheu HM, Guo YL, Lee YH, Lai CS, Pan MH, Wang YJ. Hexavalent chromium-induced ROS formation, Akt, NF-κB, and MAPK activation, and TNF-α and IL-1α production in keratinocytes. Toxicology Letters. 2011. 198(2):216-224.
2010 Wu H, Hsieh MC, Lo CY, Liu CB, Sang S, Ho CT, Pan MH*. 6-shogaol is more effective than 6-gingerol and curcumin in inhibiting 12-Otetradecanoylphorbol-13-acetate-induced tumor promotion in mice. Molecular Nutrition and Food Research. 2011. 54(9):1296-1306.
2010 Chiou YS, Tsai ML, Wang YJ, Cheng AC, Lai WM, Badmaev V, Ho CT, Pan MH*. Pterostilbene inhibits colorectal aberrant crypt foci (ACF) and colon carcinogenesis via suppression of multiple signal transduction pathways in azoxymethane-treated mice. Journal of Agricultural and Food Chemistry. 2011. 58(15):8833-8841.
2010 Huang CY, Chen JY, Wu JE, Pu YS, Liu GY, Pan MH, Huang YT, Huang AM, Hwang CC, Chung SJ, Hour TC. Ling-Zhi Polysaccharides Potentiate Cytotoxic Effects of Anticancer Drugs against Drug-Resistant Urothelial Carcinoma Cells. Journal of Agricultural and Food Chemistry. 2010. 58(15):8798-8805.
2010 Wang BJ, Guo YL, Chang HY, Sheu HM, Pan MH, Lee YH, Wang YJ. N-acetylcysteine inhibits chromium hypersensitivity in coadjuvant chromium-sensitized albino guinea pigs by suppressing the effects of reactive oxygen species. Experimental Dermatology. 2010. 19(8):191-200.
2010 Qiu P, Dong P, Guan H, Li S, Ho CT, Pan MH, McClements DJ, Xiao H. Inhibitory effects of 5-hydroxy polymethoxyflavones on colon cancer cells. Molecular Nutrition and Food Research. 2010. 54:1-9.
2010 Shen D, Pan MH, Wu QL, Park CH, Juliani HR, Ho CT, Simon JE. LC-MS Method for the Simultaneous Quantitation of the Anti-inflammatory Constituents in Oregano (Origanum Species). Journal of Agricultural and Food Chemistry. 2010. 58(12):7119-7125.
2010 Bai N, He K, Roller M, Lai CS, Shao X, Pan MH, Ho CT. Flavonoids and phenolic compounds from Rosmarinus officinalis. Journal of Agricultural and Food Chemistry. 2011. 58(9):5363-5367.
2010 Kuo DH, Lai YS, Lo CY, Cheng AC, Wu H, Pan MH*. Inhibitory effect of magnolol on TPA-induced skin inflammation and tumor promotion in mice. Journal of Agricultural and Food Chemistry. 2010. 58(9):5777-5783.
2010 Shieh PC, Chen YO, Kuo DH, Chen FA, Tsai ML, Chang IS, Wu H, Sang S, Ho CT, Pan MH*. Induction of apoptosis by [8]-shogaol via reactive oxygen species generation, glutathione depletion, and caspase activation in human leukemia cells. Journal of Agricultural and Food Chemistry. 2010. 58(6):3847-3854.
2010 Bai N, He K, Zhou Z, Tsai ML, Zhang L, Quan Z, Shao X, Pan MH, Ho CT. Ent-kaurane diterpenoids from Rabdosia rubescens and their cytotoxic effects on human cancer cell lines. Planta Medica. 2010. 76(2):140-145.
2010 Lo YH, Pan MH, Li S, Yen JH, Kou MC, Ho CT, Wu MJ. Nobiletin metabolite, 3′,4′-dihydroxy-5,6,7,8-tetramethoxyflavone,inhibits LDL oxidation and down-regulates scavenger receptor expression and activity in THP-1 cells. Biochimica et Biophysica Acta. 2010. 1801(2):114-126.
2010 Pan MH*, Lin CL, Tsai JH, Ho CT, Chen WJ. 3,5,3’,4’,5’-Pentamethoxystilbene (MR-5), a Synthetically Methoxylated Analogue of Resveratrol, Inhibits Growth and Induces G1 Cell Cycle Arrest of Human Breast Carcinoma MCF-7 Cells. Journal of Agricultural and Food Chemistry. 2010. 58(1):226-234.
2010 Shih YL, Liu HC, Chen CS, Hsu CH, Pan MH, Chang HW, Chang CH, Chen FC, Ho CT, Yang YY, Ho YS. Combination treatment with luteolin and quercetin enhances antiproliferative effects in nicotine-treated MDA-MB-231 cells by down-regulating. Journal of Agricultural and Food Chemistry. 2010. 58(1):235-241.
2009 Kuo YC, Lai CS, Wang JM, Badmaev V, Nagabhushanam K, Ho CT, Pan MH*. Differential inhibitory effects of inotilone on inflammatory mediators, inducible nitric oxide synthase and cyclooxygenase-2, in LPS stimulated murine macrophage. Molecular Nutrition and Food Research. 2009. 53(11):1386-1395.
2009 Lai CS, Lee JH, Ho CT, Liu CB, Wang JM, Wang YJ, Pan MH*. Rosmanol potently inhibits lipopolysaccharide-induced iNOS and COX-2 expression through downregulating MAPK, NF-kappaB, STAT3 and C/EBP signaling pathways. Journal of Agricultural and Food Chemistry. 2009. 57(22):10990-10998.
2009 Sang S, Hong J, Wu H, Liu J, Yang CS, Pan MH, Badmaev V, Ho CT. Increased growth inhibitory effects on human cancer cells and anti-inflammatory potency of shogaols from Zingiber officinale relative to gingerols. Journal of Agricultural and Food Chemistry. 2009. 57(22):10645-10650.
2009 Huang CH, Tsai SJ, Wang YJ, Pan MH, Kao JY, Way TD. EGCG inhibits protein synthesis, lipogenesis, and cell cycle progression through activation of AMPK in p53 positive and negative human hepatoma cells. Molecular Nutrition and Food Research. 2009. 53(9):1156-1165.
2009 Pan, MH.*; Chiou, YS.; Chen, WJ.; Wang, JM.; Badmaev, V, Ho, CT. Pterostilbene inhibited tumor invasion via suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells. Carcinogenesis. 2009. 30(7):1234-1242.
2009 Pan, MH*, Lai, CS.; Dushenkov, S, Ho, CT. Modulation of inflammatory genes by natural dietary bioactive compounds. Journal of Agricultural and Food Chemistry. 2009. 57 (11):4467-4477.
2009 Pan, MH.*; Yang, JR.; Tsai, ML.; Sang, S, Ho, CT. Anti-inflammatory effect of Momordica grosvenori Swingle extract through suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 inmurine macrophages. Journal of Functional Foods. 2009. 1(2):145-152.
2009 Li S, Pan, MH., Lo CY, Tan D, Wang Y, Shahidi F, Ho CT. Chemistry and health effects of polymethoxyflavones and hydroxylated polymethoxyflavones. Journal of Functional Foods. 2009. 1(1):2-12.
2008 Li, S, Pan, MH, Wang, Z, Lambros, T, Ho, CT. Biological activity, metabolism and separation of polymethoxyflavones from citrus peels. Tree and Forestry Science and Biotechnology. 2008. 2:36-51.
2008 Pan, MH, Ho, CT. Chemopreventive effects of natural dietary compounds on cancer development. Chemical Society Reviews. 2008. 37(11):2558-2574.
2008 Lai, CS, Li, S, Chai, CY, Lo, CY, Dushenkov, S, Ho, CT, Pan, MH, Wang, YJ. Anti-inflammatory and antitumor promotional effects of a novel urinary metabolite, 3',4'-didemethylnobiletin, derived from nobiletin. Carcinogenesis. 2008. 29(12):2415-2424.
2008 Pan, MH, Chang, YH, Tsai, ML, Lai, CS.; Ho, SY, Badmaev, V, Ho, CT. Pterostilbene suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 in murine macrophages. Journal of Agricultural and Food Chemistry. 2008. 56(16):7502-7509.
2008 Wang, YJ, Yang, MC, Pan, MH. Dihydrolipoic acid inhibits tetrachlorohydroquinone -induced tumor promotion through prevention of oxidative damage. Food and Chemical Toxicol. 2008, 46(12):3739-3748.
2008 Pan, MH, Hsieh, MC, Hsu, PC, Ho, SY, Lai, CS, Wu, H, Sang, S, Ho, CT. 6-Shogaol suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 in murine macrophages. Molecular Nutrition & Food Research. 2008. 52(12):1467-1477.
2008 Chen, SH, Lin, JK, Liang, YC, Pan, MH, Liu, SH, Lin-Shiau, SY. Involvement of activating transcription factors JNK, NF-kappaB, and AP-1 in apoptosis induced by pyrrolidine dithiocarbamate/Cu complex. European Journal of Pharmacology. 2008. 594(1-3):9-17.
2008 Chen, WJ, Huang, YT, Wu, ML, Huang, TC, Ho, CT, Pan, MH. Induction of apoptosis by vitamin D2, ergocalciferol, via reactive oxygen species generation, glutathione depletion, and caspase activation in human leukemia Cells. Journal of Agricultural and Food Chemistry. 2008. 56(9):2996-3005.
2008 Lee, SW, Pan, MH, Chen, CM, Chen, ZT. Withangulatin I, a new cytotoxic withanolide from Physalis angulata. Chemical and Pharmaceutical Bulletin (Tokyo). 2008. 56(2):234-236.
2008 Pan, MH*, Ghai, G, Ho, CT. Food bioactives, apoptosis, and cancer. Molecular Nutrition & Food Research. 2008. 52(1):43-52.
2008 Pan, MH*, Hsieh, MC, Kuo, JM, Lai, CS, Wu, H, Sang, S, Ho, CT. 6-Shogaol induces apoptosis in human colorectal carcinoma cells via ROS production, caspase activation, and GADD 153 expression. Molecular Nutrition & Food Research. 2008. 52(5):527-537.
2008 Lo, CY, Li, SM, Wang, Y, Tan, D, Pan, MH, Sang, SM, Ho, CT. Reactive Dicarbonyl Compounds and 5-(Hydroxymethyl)-2-furfural in Carbonated Beverages Containing High Fructose Corn Syrup. Food Chemistry. 2008. 107:1099-1105.
2008 Pan, MH, Chen, CM, Lee, SW, Chen, ZT. Cytotoxic triterpenoids from the root bark of Helicteres angustifolia. Chemistry Biodiversity. 2008. 5(4):565-574.
2008 Tseng, LH, Li, MH, Tsai, SS, Lee, CW, Pan, MH, Yao, WJ, Hsu, PC. Developmental exposure to decabromodiphenyl ether (PBDE 209): effects on thyroid hormone and hepatic enzyme activity in male mouse offspring. Chemosphere. 2008. 70(4):640-647.
2008 Pan, MH, Gao, JH, Lai, CS, Wang, YJ, Chen, WM, Lo, CY, Wang, M, Dushenkov, S, Ho, CT. Antitumor activity of 3,5,4'-trimethoxystilbene in COLO 205 cells and xenografts in SCID mice. Molecular Carcinogensis. 2008. 47(3):184-196.
2007 Lai, CS, Li, S, Chai, CY, Lo, CY, Ho, CT, Wang, YJ, Pan, MH.* Inhibitory effect of citrus 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone on 12-O-tetradecanoylphorbol 13-acetate-induced skin inflammation and tumor promotion in mice. Carcinogenesis. 2007. 28(12):2581-2588.
2007 Pan, MH, Chang, YH, Badmaev, V, Nagabhushanam, K, Ho, CT. Pterostilbene induces apoptosis and cell cycle arrest in human gastric carcinoma cells. Journal of Agricultural and Food Chemistry. 2007. 55(19):7777-7785.
2007 Li, S, Sang, S, Pan, MH, Lai, CS, Lo, CY, Yang, CS, Ho, CT. Anti-inflammatory property of the urinary metabolites of nobiletin in mouse. Bioorganic Medicinal Chemistry Letters. 2007. 17(18): 5177-5181.
2007 Chen, CR, Cheng, CW, Pan, MH, Liao, YW, Tzeng, CY, Chang, CI. Lanostane-type triterpenoids from Diospyros discolor. Chemical and Pharmaceutical Bulletin (Tokyo). 2007. 55(6):908-911.
2007 Pan, MH, Lin, CC, Lin, JK, Chen, WJ. Tea polyphenol (-)-epigallocatechin 3-gallate suppresses heregulin-beta1-induced fatty acid synthase expression in human breast cancer cells by inhibiting phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase cascade signaling. Journal of Agricultural and Food Chemistry. 2007. 55(13):5030-5037.
Hsu, PC, Pan, MH, Li, LA, Chen, CJ, Tsai, SS, Guo, YL. Exposure in utero to 2,2',3,3',4,6'-hexachlorobiphenyl (PCB 132) impairs sperm function and alters testicular apoptosis-related gene expression in rat offspring. Toxicology and Applied Pharmacology. 2007. 221(1):68-75.
2007 Pan, MH, Huang, YT, Chang, CI, Ho, CH, Pan, BS. Apoptotic-inducing epidioxysterols identified in Hard Clam. Food Chemistry. 2007. 102:788-795.
2007 Pan, MH, Chiou, YS, Cheng, AC, Bai, N, Lo, CY, Tan, D, Ho, CT. Involvement of MAPK, Bcl-2 family, cytochrome c, and caspases in induction of apoptosis by 1,6-O, O-diacetylbritannilactone in human leukemia cells. Molecular Nutrition & Food Research. 2007. 51(2):229-238.
2007 Huang, TC, Fu, HY, Ho, CT, Huang, YH, Pan, MH. Induction of apoptosis by cinnamaldehyde from indigenous cinnamon Cinnamomum osmophloeum Kaneh through reactive oxygen species production, glutathione depletion, and caspase activation in human leukemia K562 cells. Food Chemistry. 2007. 103:434-443.
2007 Chen, CR, Chao, LH, Pan, MH, Liao, YW, Chang, CI. Tocopherols and Triterpenoids from Sida acuta. Journal of the Chinese Chemical Society. 2007. 54:41-45.
2007 Li, S, Pan, MH, Lai, CS, Lo, CY, Dushenkov, S, Ho, CT. Isolation and syntheses of polymethoxyflavones and hydroxylated polymethoxyflavones as inhibitors of HL-60 cell lines. Bioorganic & Medicnal Chemistry. 2007. 15(10):3381-3389.
2007 Pan, MH, Lai, YS, Lai, CS, Wang, YJ, Li, S, Lo, CY, Dushenkov, S, Ho, CT. 5-Hydroxy-3,6,7,8,3',4'-hexamethoxyflavone induces apoptosis through reactive oxygen species production, growth arrest and DNA damage-inducible gene 153 expression, and caspase activation in human leukemia cells. Journal of Agricultural and Food Chemistry. 2007. 55(13):5081-5091.
2007 Ho, YS, Lai, CS, Liu, HI, Ho, SY, Tai, C, Pan, MH, Wang, YJ. Dihydrolipoic acid inhibits skin tumor promotion through anti-inflammation and anti-oxidation. Biochemical Pharmacology. 2007. 73(11):1786-1795.
2007 Cheng, AC, Jian, CB, Huang, YT, Lai, CS, Hsu, PC, Pan, MH. Induction of apoptosis by Uncaria tomentosa through reactive oxygen species production, cytochrome c release, and caspases activation in human leukemia cells. Food Chemical Toxicol. 2007. 45(11):2206-2218.
2007 Pan, MH*, Lai, CS, Ho, CT. Antioxidant activity of phytopolyphenols: Assessment in cell culture systems. ACS Symposium Series. 2007. 956:92-105.
2006 Lo, CY, Li, S, Tan, D, Pan, MH, Sang, S, Ho, CT. Trapping reactions of reactive carbonyl species with tea polyphenols in simulated physiological conditions. Molecular Nutrition & Food Research. 2006. 50(12):1118-1128.
2006 Pan, MH*, Lai, CS, Wang, YJ, Ho, CT. Acacetin suppressed LPS-induced up-expression of iNOS and COX-2 in murine macrophages and TPA-induced tumor promotion in mice. Biochemical Pharmacology. 2006. 72(10):1293-1303.
2006 Tseng, LH, Lee, CW, Pan, MH, Tsai, SS, Li, MH, Chen, JR, Lay, JJ, Hsu, PC. Postnatal exposure of the male mouse to 2,2',3,3',4,4',5,5',6,6'-decabrominated diphenyl ether: decreased epididymal sperm functions without alterations in DNA content and histology in testis. Toxicology. 2006. 224(1-2):33-43.
2006 Kuo, JM, Hwang, A, Yeh, DB, Pan, MH, Tsai, ML, Pan, BS. Lipoxygenase from banana leaf: purification and characterization of an enzyme that catalyzes linoleic acid oxygenation at the 9-position. Journal of Agricultural and Food Chemistry. 2006. 54(8):3151-3156.
2006 Cheng, AC, Huang, TC, Lai, CS, Kuo, JM, Huang, YT, Lo, CY, Ho, CT, Pan, MH. Pyrrolidine dithiocarbamate inhibition of luteolin-induced apoptosis through up-regulated phosphorylation of Akt and caspase-9 in human leukemia HL-60 cells. Journal of Agricultural and Food Chemistry. 2006. 54(12):215-4221.
2006 Pan, MH, Huang, YT, Ho, CT, Chang, CI, Hsu, PC, Sun, PB. Induction of apoptosis by Meretrix lusoria through reactive oxygen species production, glutathione depletion, and caspase activation in human leukemia cells. Life Sciences. 2006. 79(12):1140-1152.
2006 Huang, YT, Huang, YH, Hour, TC, Pan, BS, Liu, YC, Pan, MH. Apoptosis-inducing active components from Corbicula fluminea through activation of caspase-2 and production of reactive oxygen species in human leukemia HL-60 cells. Food Chemical Toxicol. 2006. 44(8):1261-1272.
2006 Bai, N, Lai, CS, He, K, Zhou, Z, Zhang, L, Quan, Z, Zhu, N, Zheng, QY, Pan, MH, Ho, CT. Sesquiterpene lactones from Inula britannica and their cytotoxic and apoptotic effects on human cancer cell lines. Journal of Natural Products. 2006. 69(4):531-535.
2006 Hsu, PC, Chen, IY, Pan, CH, Wu, KY, Pan, MH, Chen, JR, Chen, CJ, Chang-Chien, GP, Hsu, CH, Liu, CS, Wu, MT. Sperm DNA damage correlates with polycyclic aromatic hydrocarbons biomarker in coke-oven workers. International Archives of Occupational and Environmental Health. 2006. 79(5):349-356.
2006 Huang, TC, Ho, CT, Fu, HY, Pan, MH. Cytotoxic properties of leaf essential oil and components from indigenous cinnamon (Cinnamomum osmophloeum Kaneh). Herbs: Challenges in Chemistry and Biology. 2006. 925:299-313.
2005 Pan, MH, Sin, YH, Lai, CS, Wang, YJ, Lin, JK, Wang, M, Ho, CT. Induction of apoptosis by 1-(2-hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione through reactive oxygen species production, GADD153 expression, and caspases activation in human epidermoid carcinoma cells. Journal of Agricultural and Food Chemistry. 2005. 53(23):9039-9049.
2005 Cheng, AC, Huang, TC, Lai, CS, Pan, MH. Induction of apoptosis by luteolin through cleavage of Bcl-2 family in human leukemia HL-60 cells. European Journal of Pharmacology. 2005. 509(1):1-10.
2005 Pan, MH, Lai, CS, Hsu, PC, Wang, YJ. Acacetin induces apoptosis in human gastric carcinoma cells accompanied by activation of caspase cascades and production of reactive oxygen species. Journal of Agricultural and Food Chemistry. 2005. 53(3):620-630.
2005 Yen, RF, Wu, YW, Pan, MH, Tzen, KY. Early detection of splenic metastasis of lung cancer by F-18-2-fluoro-2-deoxyglucose positron emission tomography. Journal of the Formosan Medical Association. 104(9): 674-676.
2004 Hsu, PC, Huang, YT, Tsai, ML, Wang, YJ, Lin, JK, Pan, MH. Induction of apoptosis by shikonin through coordinative modulation of the Bcl-2 family, p27, and p53, release of cytochrome c, and sequential activation of caspases in human colorectal carcinoma cells. Journal of Agricultural and Food Chemistry. 2004. 52(20):6330-6337.
2004 Lin, YP, Zhu, BZ, Yang, MC, Frei, B, Pan, MH, Lin, JK and Wang, YJ. Bcl-2 Overexpression Inhibits Tetrachlorohydroquinone-Induced Apoptosis in NIH3T3 Cells: A Possible Mechanism for Tumor Promotion. Molecular Carcinogenesis. 2004. 40(1):24-33.
2003 Pan, MH, Huang, MC, Wang, YJ, Lin, JK, Lin, CH. Induction of apoptosis by hydroxydibenzoylmethane through coordinative modulation of cyclin D3, Bcl-X(L), and Bax, release of cytochrome c, and sequential activation of caspases in human colorectal carcinoma cells. Journal of Agricultural and Food Chemistry. 2003. 51(14):3977-3984.
2003 Lin, JK, Pan, MH, Ho, CT, Lin-Shiau, SY. Cancer chemoprevention by phytopolyphenols through modulating mitotic and differentiating signal transduction pathways. Food Factors in Health Promotion and Disease Prevention. 2003. 851: 50-71.
2002 Pan, MH, Chen, WJ, Lin-Shiau, SY, Ho, CT, Lin, JK. Tangeretin induces cell-cycle G1 arrest through inhibiting cyclin-dependent kinases 2 and 4 activities as well as elevating Cdk inhibitors p21 and p27 in human colorectal carcinoma cells. Carcinogenesis. 2002. 23(10):1677-1684.
2002 Ho, YS, Liou, HB, Lin, JK, Jeng, JH, Pan, MH, Lin, YP, Guo, HR, Ho, SY, Lee, CC, Wang, YJ. Lipid peroxidation and cell death mechanisms in pulmonary epithelial cells induced by peroxynitrite and nitric oxide. Archives of Toxicology. 2002. 76(8):484-493.
2001 Sang, S, Pan, MH, Cheng, X, Bai, N, Stark, RE, Rosen, RT, Lin-Shiau, SY, Lin, JK, Ho, CT. Chemical studies on antioxidant mechanism of garcinol: analysis of radical reaction products of garcinol and their antitumor activities. Tetrahedron. 2001. 57:9931-9938.
2001 Pan, MH, Chang, WL, Lin-Shiau, SY, Ho, CT, Lin, JK. Induction of apoptosis by garcinol and curcumin through cytochrome c release and activation of caspases in human leukemia HL-60 cells. Journal of Agricultural and Food Chemistry. 2001. 49(3):1464-1474.
2001 Cheng, AL, Hsu, CH, Lin, JK, Hsu, MM, Ho, YF, Shen, TS, Ko, JY, Lin, JT, Lin, BR, Ming-Shiang, W, Yu, HS, Jee, SH, Chen, GS, Chen, TM, Chen, CA, Lai, MK, Pu, YS, Pan, MH, Wang, YJ, Tsai, CC, Hsieh, CY. Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. Anticancer Research. 2001. 21(4B):2895-2900.
2000 Lin, JK, Pan, MH, Lin-Shiau, S. Y. Recent studies on the biofunctions and biotransformations of curcumin. Biofactors. 2000. 13(1-4):153-158.
2000 Pan, MH, Liang, YC, Lin-Shiau, SY, Zhu, NQ, Ho, CT, Lin, JK. Induction of apoptosis by the oolong tea polyphenol theasinensin A through cytochrome c release and activation of caspase-9 and caspase-3 in human U937 cells. Journal of Agricultural and Food Chemistry. 2000. 48(12):6337-6346.
2000 Pan, MH, Lin-Shiau, SY, Lin, JK. Comparative studies on the suppression of nitric oxide synthase by curcumin and its hydrogenated metabolites through down-regulation of IkappaB kinase and NFkappaB activation in macrophages. Biochemical Pharmacology. 2000. 60(11):1665-1676.
2000 Pan, MH, Lin-Shiau, SY, Ho, CT, Lin, JH, Lin, JK. Suppression of lipopolysaccharide-induced nuclear factor-kappaB activity by theaflavin-3,3'-digallate from black tea and other polyphenols through down-regulation of IkappaB kinase activity in macrophages. Biochemical Pharmacology. 2000. 59(4):357-367.
1999 Pan, MH, Lin, JH, Lin-Shiau, SY, Lin, JK. Induction of apoptosis by penta-O-galloyl-beta-D-glucose through activation of caspase-3 in human leukemia HL-60 cells. European Journal of Pharmacology. 1999. 381(2-3):171-183.
1999 Pan, MH, Huang, TM, Lin, JK. Biotransformation of curcumin through reduction and glucuronidation in mice. Drug Metabolism & Disposition. 1999. 27(4):486-494.
1998 Wang, YJ, Ho, YS, Pan, MH, Lin, JK. Mechanisms of cell death induced by nitric oxide and peroxynitrite in Calu-1 cells. Environmental Toxicology and Pharmacology. 1998. 6(1):35-44.
1997 Wang, YJ, Pan, MH, Cheng, AL, Lin, LI., Ho, YS, Hsieh, CY, Lin, JK. Stability of curcumin in buffer solutions and characterization of its degradation products. Journal of Pharmaceutical and Biomedical Analysis. 1997. 15(12):1867-1876.
1997 Kong, ZL, Chiang, LC, Fang, F, Shinohara, K, Pan, P. Immune bioactivity in shellfish toward serum-free cultured human cell lines. Bioscience, Biotechnology, and Biochemistry. 1997. 61(1):24-28.
2019 Chi-Tang Ho, Shiming Li, Min-Hsiung Pan*. Polymethoxyflavones from citrus peels as anti-obesity functional food ingredients. The 7th International Conference on Food Factors (ICoFF2019) and the 12th International Conference and Exhibition on Nutraceuticals and Functional Foods, Dec 01-05, 2019. Kobe, Japan.
2019 Yi-Shiou Chiou, Yike Jiang, Chi-Tang Ho, Min-Hsiung Pan*. (-)-Epicatechin-3-gallate ameliorates sepsis-induced acute organ injuries and mortality via upregulation of Nrf2-regulated antioxidant effects. The 7th International Conference on Food Factors (ICoFF2019) and the 12th International Conference and Exhibition on Nutraceuticals and Functional Foods, Dec 01-05, 2019. Kobe, Japan.
2019 Wei-Sheng Lin, Nai-Wen Mei, Min-Hsiung Pan*. Alkaline hydrolysates of ginseng extract to enhance cancer chemoprevention activity. The 7th International Conference on Food Factors (ICoFF2019) and the 12th International Conference and Exhibition on Nutraceuticals and Functional Foods, Dec 01-05, 2019. Kobe, Japan.
2019 Ya-Chun Chou, Pin-Yu Ho, Min-Hsiung Pan*. Lactobacillus fermentum ameliorates colitis-associated tumorigenesis by modulating gut microbiome. The 7th International Conference on Food Factors (ICoFF2019) and the 12th International Conference and Exhibition on Nutraceuticals and Functional Foods, Dec 01-05, 2019. Kobe, Japan.
2019 Min-Hsiung Pan*, Chia-Ching Wu, and Chi-Tang Ho. Chemopreventive effect of natural dietary compounds on xenobiotic induced carcinogenesis. The 7th International Conference on Food Factors (ICoFF2019) and the 12th International Conference and Exhibition on Nutraceuticals and Functional Foods, Dec 01-05, 2019. Kobe, Japan.
2019 Pei-Sheng Lee, Yi-Shiou Chiou, Nagabhushanam Kalyanam, Chi-Tang Ho, Min-Hsiung Pan*. Chemopreventive efficacy of 3-hydroxypterostilbene on suppression of high fat diet-induced obesity promotes colitis. The 7th International Conference on Food Factors (ICoFF2019) and the 12th International Conference and Exhibition on Nutraceuticals and Functional Foods, Dec 01-05, 2019. Kobe, Japan.
2019 Ching-Shu Lai, Jing-Ru Lin, Mei-Ling Tsai, Min-Hsiung Pan, Chi-Tang Ho. Calebin-A improved adipose inflammation and insulin resistance in dietinduced obesity. The 7th International Conference on Food Factors (ICoFF2019) and the 12th International Conference and Exhibition on Nutraceuticals and Functional Foods, Dec 01-05, 2019. Kobe, Japan.
2019 Yi-Zhen Tsai, Chi-Tang Ho, Min Hsiung Pan, Ching-Shu Lai. The effect of Tetrahydrocurcumin inhibits TNF-α induced insulin resistant. The 7th International Conference on Food Factors (ICoFF2019) and the 12th International Conference and Exhibition on Nutraceuticals and Functional Foods, Dec 01-05, 2019. Kobe, Japan.
2019 Yen-Chen Tung, Zhi-Rong Liang, Chi-Tang Ho, Kuan-Chen Cheng, Ting-Jang Lu, Min-Hsiung Pan*. The effect of miso on non-alcoholic fatty liver and modulated gut microbiota in high fat diet fed rats. The 7th International Conference on Food Factors (ICoFF2019) and the 12th International Conference and Exhibition on Nutraceuticals and Functional Foods, Dec 01-05, 2019. Kobe, Japan.
2018 Yen-Chen Tung, Rou-Fong Chou, Chi-Tang Ho, Min-Hsiung Pan*. Anti-obesity efficacy of isoflavones daidzein and genistein and their derivatives in vitro and in vivo. The 19th IUFoST World Food Science and Technology Congress, Oct 23-27, 2018. Mumbai, India.
2018 Min-Hsiung Pan*, Chia-Ching Wu, Ying-Jan Wang, and Chi-Tang Ho. Polymethoxyflavones prevent benzo[a]pyrene/dextran sodium sulfate-induced colorectal carcinogenesis through modulating xenobiotic metabolism in ICR mice. 54th Eurotox Annual Meeting Brussels, Belgium, Aug 31-Sep 9, 2018. Brussels Belgium.
2018 Min-Hsiung Pan*. Polymethoxyflavones prevent benzo[a]pyrene/dextran sodium sulfate-induced colorectal carcinogenesis in mice. THE 10th INTERNATIONAL SYMPOSIUM OF FOOD SCIENCE, Aug 1-7, 2018. Heilongjiang, China.
2018 Yi-Shiou Chiou, Yi-Ting Hsiao, Chi-Tang Ho, Min-Hsiung Pan*. Piceatannol reinforces the Nrf2 antioxidant defense improves carbon tetrachloride-induced hepatotoxicity. 5th Healthcare Economics, Technology and Management Conference and Expo, Aug 24-26, 2018. Copenhagen, Denmark.
2018 Min-Hsiung Pan*. Polymethoxyflavones prevent benzo[a]pyrene/dextran sodium sulfate-induced colorectal carcinogenesis through modulating xenobiotic metabolism and ameliorate autophagic defect in ICR mice. 19th International Congress on NUTRITION & HEALTH, Apr 12-14, 2018. Amsterdam, Netherlands. (Organizing Committee)
2017 Min-Hsiung Pan*, Chia-Ching Wu, Ching-Shu Lai, and Chi-Tang Ho. Chemopreventive effects of natural dietary compounds on human disease. The International Society for Nutraceuticals and Functional Foods (ISNFF) Conference, Oct 22-25, 2017. Gunsan, Jeonbuk, Korea. (Invited Speaker and Chairperson)
2017 Jia-Ching Wu, Mei-Ling Tsai, Ching-Shu Lai, Chi-Tang Ho, Ying-Jan Wang and Min-Hsiung Pan*. Polymethoxyflavones prevent benzo[a]pyrene/dextran sodium sulfate-induced colorectal carcinogenesis through modulate xenobiotic metabolism and improve autophagic defect in ICR mice. The International Society for Nutraceuticals and Functional Foods (ISNFF) Conference, Oct 22-25, 2017. Gunsan, Jeonbuk, Korea, P1-99.
2017 Yen-Chen Tung, Wei-Tien Chang, Jia-Ching Wu, Wei-Lun Hung, Chi-Tang Ho, and Min-Hsiung Pan*. Citrus peel extracts attenuated obesity and altered gut microbiota in high fat diet induced obese animal model. The International Society for Nutraceuticals and Functional Foods (ISNFF) Conference, Oct 22-25, 2017. Gunsan, Jeonbuk, Korea, P3-113.
2017 Rong-Jane Chen, Pei-Hsuan Wu, Chi-Tang Ho, Min-Hsiung Pan, Yuan-Soon Ho, and Ying-Jan Wang*. P53-dependent down-regulation of hTERT protein expression and telomerase activity induces senescence in lung cancer cells as a result of pterostilbene treatment. The International Society for Nutraceuticals and Functional Foods (ISNFF) Conference, Oct 22-25, 2017. Gunsan, Jeonbuk, Korea.
2017 Pei-Sheng Lee, Chia-Yi Teng, Kun-Feng Hsieh, Nagabhushanam Kalyanam, Chi-Tang Ho and Min-Hsiung Pan*. Garcinol reduces obesity in C57BL/6 mice by modulating the composition of the gut microbiota. 3rd Global Summit on Herbals Traditional Medicine, Oct 18-20, 2017. Osaka, Japan.
2017 Yi-Shiou Chiou, Chi-Tang Ho and Min-Hsiung Pan*. Garcinol sensitizes breast cancer cells to Taxol through suppression of caspase-3/IPLA2 and NF-κB/Twist1 signaling pathways in mouse 4T1 breast tumor model. 3rd Global Summit on Herbals Traditional Medicine, Oct 18-20, 2017. Osaka, Japan.
2017 Min-Hsiung Pan*, Yen-Chen Tung, Nagabhushanam Kalyanam, Yu-Hsuan Lin, Chi-Tang Ho. Piceatannol exerts anti-obesity effects through modulating adipogenic proteins and gut microbiota in C57BL/6 mice. Joint OCC World Congress & Annual SFRR-E Conference 2017 - Metabolic stress and redox regulation. Jun 21-23, 2017. Berlin, Germany.
2016 Min-Hsiung Pan*. Chemopreventive effects of polymethoxyflavones on cancer development. The International Society for Nutraceuticals and Functional Foods (ISNFF) Conference, Oct 9-13, 2016. Orlando, Florida, USA. (Oral Presentation and Moderator)
2016 Min-Hsiung Pan* and Chi-Tang Ho. Chemopreventive effects of stilbenoids on colon cancer development. BIT’s 9th Annual World Cancer Congress -2016, May 14-16, 2016. Shanghai, China.
2015 Min-Hsiung Pan*, Ching-Shu Lai, Chih-Yu Lo, Shiming Li and Chi-Tang Ho. Molecular mechanisms of disease chemoprevention by polymethoxyflavones. 205th ACS National Meeting , Aug 16-20, 2015. Boston, Massachusetts, USA. (Chairperson and Oral Presentation) Symposium Committee on Polymethoxyflavone Division of Agricultural and Food Chemistry.
2015 Min-Hsiung Pan*. Chemopreventive effects of dietary natural compounds on inflammation-associated human disease. 2nd International Symposium of Food Science and Human Wellness. July 25-26, 2015. Zhuzhou, Hunan, China. (Chairperson and Oral Presentation)
2015 Ming-Yi Li, Mei-Ling Tsai, Vladimir Badmaev, Chi-Tang Ho and Ming-Hsiung Pan*. PLGE inhibited adipogenesis and obesity through activated AMPK signaling pathway in 3T3-L1 preadipocytes and high fat diet-induced obesity. The 6th International Conference on Food Factors 2015 (ICoFF 2015), Nov 22-25, 2015. Seoul, Republic of Korea, P-0383, P112
2015 Jia-Ching Wu, Fang-Zong Wang, Mei-Ling Tsai, Chih-Yu Lo, Vladimir Badmaev, Chi-Tang Ho, Ying-Jan Wang, Min-Hsiung Pan*. Se-allylselenocystein induced autophagy and cell cycle arrest through modulated PCDH17 promoter hypomethlation state and AMPK signaling pathway in HT-29 cell line. The 6th International Conference on Food Factors 2015 (ICoFF 2015), Nov 22-25, 2015. Seoul, Republic of Korea, P-0159, P77
2015 Jia-Ching Wu, Vladimir Badmaev, Chi-Tang Ho, Ying-Jan Wang, Min-Hsiung Pan*. (2015). Selenium-conjugated compound induce autophagic cell death through modulating PCDH17 expression by epigenetic regulation in HT-29 human colon cancer cell line. The 8th Internatiional Conference and Exhibition for Nutraceuticals and Functional Foods (ISNFF), Sep 20-23, 2015. Wuxi, China.
2015 Min-Hsiung Pan*, Tzu-Chun Cheng, Ching-Shu Lai, Min-Ching Chung, Chi-Tang Ho, Yuan-Soon Ho. Potent anti-cancer effect of 3'-hydroxypterostilbene in human colon xenograft tumors. (Eurotox 2015) 51th Congress of the European Societies of Toxicology, Sep 13-16, 2015. Porto, Portugal.
2014 Fang-Zong Wang, Jia-Ching Wu, Mei-Ling Tsai, Min-Hsiung Pan. Se-allyl- selenocysteine induced autophagy through modulating epigenetic mechanism in human colorectal adenocarcinoma HT-29 cells. Taiwan association of food science technology, Dec 5, 2014. National Kaohsiung Marine University, Kaohsiung, 811, Taiwan, No. 61.
2014 Ming-Yi Lo, Chin-Shu Lai, Jia-Chin Wu, Chen-Yu Tsai, Min-Hsiung Pan, Mei-Ling Tsai.3’,4’-didemethylnobiletin is more effective than nobiletin suppressed lipopolysaccharide-induced iNOS and COX-2 expression through inhibit MAPK and NF-kB signaling pathways. Taiwan association of food science technology, Dec 5, 2014. National Kaohsiung Marine University, Kaohsiung, 811, Taiwan, No. 64.
2014 Chia-Jung Teng, Wen-Tuan Hsiao, Min-Hsiung Pan, Chi-Tang Ho, Chih-Yu Lo. Anti-glycation activities of immature persimmon fruit (Diospyros kaki L. cv. Bull heart) extract. Cornucopian including AGFD abstracts for the 248th American Chemical Society National Meeting, Aug 10-14, 2014. San Francisco.
2014 Shiming Li, Hui Zhao, Min-Hsiung Pan, Chih-Yu Lo, Chi-Tang Ho. Bioactive compounds in citrus fruits and chronic diseases. Cornucopian including AGFD abstracts for the 248th American Chemical Society National Meeting, Aug 10-14, 2014. San Francisco.
2014 Min-Hsiung Pan*. Cancer chemoprevention by dietary natural compounds. Cornucopian including AGFD abstracts for the 248th American Chemical Society National Meeting, Aug 10-14, 2014. San Francisco.
2014 Yuwen Ting, Yi-Shiou Chiou, Yike Jiang, Colin C Li, Pei-Ti Chen, Min-Hsiung Pan, Chi-Tang Ho, Qingrong Hunag. Toxicity evaluation for tangeretin in different oral formulations: In vivo 14-day acute and 30-day sub-chronic toxicity studies in mice. Cornucopian including AGFD abstracts for the 248th American Chemical Society National Meeting, Aug 10-14, 2014. San Francisco.
2013 Min-Hsiung Pan*, Chieh-Han Chung, and Chi-Tang Ho. 5-demethyltangeretin (5-DTAN) is more effective than tangeretin in 7,12-dimethylbenz[a]anthracene (DMBA) /12-O-Tetradecanoylphorbol -13-acetate (TPA)-induced mouse skin carcinogenesis. Eurotox 2013 Interlaken Switzerland 49th Congress of the European Societies of Toxicology, Sep 1-4, 2013. Switzerland Interlaken.
2013 Nianhan Ma, Chih-Han Chung, Tao-Sheng Chung, Shiming Li, Chi-Tang Ho, Min-Hsiung Pan*.Chemoprevention of azoxymethane-induced colonic tumorigenesis by oral administration of tangeretin and 5-demethyltangeretin. 2013AIMECS (9th AFMC International Medicinal Chemistry Symposium in 2013), Oct 15-18, 2013. Grand Hotel Taipei, Taiwan.
2013 Supatcha Janporn, Chi-Tang Ho, Visith Chavasit,Min-Hsiung Pan, Monthana Weerawatanakorn. Effect of extraction on physico-chemical properties, and shelf life study of new healthy oil from Terminalia catappa Linn seeds 2013 International Society for Nutraceuticals and Functional Foods (ISNFF), Nov 5-9, 2013. Howard Civil Service International House, Taipei, Taiwan, P25, p.145.
2013 Bi-Ni Wang, Yang Liu, Wen-Ting Lao, Tian Zhang, Min-Hsiung Pan*. Jujube extracts exhibit anti-inflammatory effects in murine RAW 264.7 cells. 2013 International Society for Nutraceuticals and Functional Foods (ISNFF), Nov 5-9, 2013. Howard Civil Service International House, Taipei, Taiwan, P185, p.226.
2013 Pei-Hsuan Hsieh, Min-Hsiung Pan*, Chi-Tang Ho*. Investigate the anti-inflammatory effect of resveratrol and its metabolite, δ-viniferin, in lipopolysaccharide-stimulated murine macrophage. 2013 International Society for Nutraceuticals and Functional Foods (ISNFF), Nov 5-9, 2013. Howard Civil Service International House, Taipei, Taiwan, P133, p.199.
2013 Sih-Ning Liao, Mei-Ling Tsai, Chi-Tang Ho, Min-Hsiung Pan*. Comparative study on the anti-inflammatory activity of polymethoxyflavones in vitro and in vivo. 2013 International Society for Nutraceuticals and Functional Foods (ISNFF), Nov 5-9, 2013. Howard Civil Service International House, Taipei, Taiwan, P186, p.226.
2013 Yu-Nu Zheng, Mei-Ling Tsai, Chi-Tang Ho, Min-Hsiung Pan*. Anti- inflammatory effect of 5-demethylnobiletin in LPS-stimulated murine macrophage and phorbol ester-treated mouse skin. 2013 International Society for Nutraceuticals and Functional Foods (ISNFF), Nov 5-9, 2013. Howard Civil Service International House, Taipei, Taiwan, P187, p.227.
2013 Su-Yao Wang, Mei-Ling Tsai, Chi-Tang Ho, Min-Hsiung Pan*. Effect of dietary administration of wheat bran extracts on azoxymethane-induced colorectal aberrant crypt foci formation in ICR mice. 2013 International Society for Nutraceuticals and Functional Foods (ISNFF), Nov 5-9, 2013. Howard Civil Service International House, Taipei, Taiwan, P188, p.227.
2013 Pei-Shiaun Chen, Shu-Me Lin, Min-Hsiung Pan, Chi-Tang Ho, Chih-Yu Lo*. Polymethoxyflavones and monodemethylated poly-methoxyflavones   inhibit adipogenesis in 3T3-L1 adipocytes. 2013 International Society for Nutraceuticals and Functional Foods (ISNFF), Nov 5-9, 2013. Howard Civil Service International House, Taipei, Taiwan.
2013 Lin, Han-Rong; Hsiao, Wen-Tuan; Pan, Min-Hsiung; Lai, Ching-Shu; Ho, Chi-Tang; Lo, Chih-Yu*. Studies on the antioxidative and anti-inflammatory activities of polyphenols from alpinia galangal. Abstracst of Papers, 245th ACS National Meeting & Exposition, Apr 7-11, 2013. New Orleans, LA, United States.
2012 Min-Hsiung Pan*, Min-Chi Hsieh and Chi-Tang Ho. Molecular targets of 6-shogaol: Its potential roles in cancer chemoprevention. INTERNATIONAL FLAVOR CONFERENCE XIII 5th GEORGE CHARALAMBOUS MEMORIAL SYMPOSIUM. 29 May - 1 June, 2012. AKS Hinitsa Bay Hotel. Porto Heli, Greece. (Oral Presentation).
2012 Yuwen Ting*, Shiming Li, Min-Hsiung Pan, Chi-Tang Ho, Qingrong Huang. Viscous emulsions enhanced bioefficacy of poorly-soluble polymethoxyflavones (PMF) in colitis-related mouse colon carcinogenesis induced by AOM/DSS. INTERNATIONAL FLAVOR CONFERENCE XIII 5th GEORGE CHARALAMBOUS MEMORIAL SYMPOSIUM. 29 May - 1 June, 2012. AKS Hinitsa Bay Hotel. Porto Heli, Greece. (Oral Presentation).
2012 Min-Hsiung Pan*, Jia-Ching Wu, Ching-Shu Lai, Vladimir Badmaev, Kalyanam Nagabhushanam and Chi-Tang Ho. Tetrahydrocurcumin (THC) potently suppresses azoxymethane-induced colon carcinogenesis in mice. INTERNATIONAL FLAVOR CONFERENCE XIII 5th GEORGE CHARALAMBOUS MEMORIAL SYMPOSIUM. 29 May - 1 June, 2012. AKS Hinitsa Bay Hotel. Porto Heli, Greece. (Oral Presentation).
2012 Yi-Shiou Chiou, Nianhan Jia-Lin Ma, Shengmin Sang, Chi-Tang Ho, Ying-Jan Wang and Min-Hsiung Pan*. Peracetylated (−)-epigallocatechin-3-gallate (AcEGCG) potently suppresses dextran sulfate sodium-induced colitis and colon tumorigenesis in mice. INTERNATIONAL FLAVOR CONFERENCE XIII 5th GEORGE CHARALAMBOUS MEMORIAL SYMPOSIUM. 29 May - 1 June, 2012. AKS Hinitsa Bay Hotel. Porto Heli, Greece. (Poster).
2012 Chieh-Han Chung, Shiming Li, Chi-Tang Ho and Min-Hsiung Pan*. Hydroxylated form of 5,6,7,8,4-pentamethoxyflavone, exhibited higher anti-tumor-promoting activity in DMBA/TPA-induced mouse skin carcinogenesis. INTERNATIONAL FLAVOR CONFERENCE XIII 5th GEORGE CHARALAMBOUS MEMORIAL SYMPOSIUM. 29 May - 1 June, 2012. AKS Hinitsa Bay Hotel. Porto Heli, Greece. (Poster).
2012 Min-Hsiung Pan*. Dietary Administration of Citrus Hydroxylated Polymethoxyflavones Inhibits Azoxymethane-induced Colon Carcinogenesis in Mice. BIT’s 5th Annual World Cancer Congress, May 18-20, 2012. Beijing International Convention Center (BICC), China. P202. (Oral Presentation).
2012 Lin, Han-Rong; Min-Hsiung Pan; Lai, Ching-Shu; Ho, Chi-Tang; Lo, Chih-Yu. Determination of antioxidative and anti-inflammatory components in Alpinia galangal. Abstract of papers, The 2012 International Society for Nutraceuticals & Functional Foods  (ISNFF), Dec 2-6, 2012. Kailua-Kona, HI, United States.
2012 Ho, Chi-Tang; Li, Shiming; Lo, Chih-Yu; Min-Hsiung Pan. Metabolites of food bioactives may exhibit stronger bioactivity. Abstracts of Papers, 243rd ACS National Meeting & Exposition, March 25-29, 2012. San Diego, CA, United States.
2011 Min-Hsiung Pan. Biological actions of garcinol on cancer chemoprevention.International Conference on Biopesticides 6 (ICOB6), Dec 11-16, 2011. Imperial Mae Ping Hotel, Chiangmai, Thailand. P137. (Oral Presentation).
2011 Min-Hsiung Pan, Ching-Shu Lai, Shiming Li, Chi-Tang Ho. Cancer chemopreventive effects of hydroxylated polymethoxyflavones on cancer development. International Conference and Exhibition on Nutraceuticals and Functional Foods. International Society for Nutraceuticals and Functional Foods (ISNFF), Nov 14-17, 2011. Royton Sapporo Hotel, Sapporo, Japan. P99, O22-3. (Oral Presentation).
2011 Min-Hsiung Pan. Ching-Shu Lai, Shiming Li, Hang Xiao, Ying-Jan Wang, Chi-Tang Ho. Chemoprevention of colonic tumorigenesis by dietary hydroxylated polymethoxyflavones in azoxymethane-treated mice. International Conference on Food Factors 2011 (ICoFF 2011) , Nov 20-23, 2011.  International Convention Center in Taipei, Taiwan, P129, S29-4. (Invited Speaker).
2011 Jia-Ching Wu, Ching-Shu Lai, Vladimir Badmaev, Kalyanam Nagabhushanam, Chi-Tang Ho, and Ming-Hsiung Pan. Effect of dietary administration of tetrahydrocurcumin and curcumin on azoxymethane-induced colorectal aberrant crypt foci formation in ICR mice. International Conference on Food Factors 2011 (ICoFF 2011) , Nov 20-23, 2011. International Convention Center in Taipei, Taiwan, P182, P1-51.
2011 Li-Yu Chiou, Chi-Tang Ho, and Ming-Hsiung Pan. Dietary supplementation of garcinol inhibits colitis-associated colorectal carcinogenesis in mice. International Conference on Food Factors 2011 (ICoFF 2011) , Nov 20-23, 2011. International Convention Center in Taipei, Taiwan, P182, P1-52.
2011 Fang-Ling Guo, Chi-Tang Ho, and Ming-Hsiung Pan. Se-methyl-L-selenocysteine (MSC) induced apoptosis through mitochondrial and JNK signaling pathways in human colon adenocarcinoma COLO 205 cells. International Conference on Food Factors 2011 (ICoFF 2011) , Nov 20-23, 2011. International Convention Center in Taipei, Taiwan, P182, P1-53.
2011 Min-Ching Chung, Chi-Tang Ho, and Ming-Hsiung Pan. Differential effects of pterostilbene and 3'-hydroxylpterostilbene on apoptosis and autophagy in human colon cancer cells COLO205. International Conference on Food Factors 2011 (ICoFF 2011) , Nov 20-23, 2011. International Convention Center in Taipei, Taiwan, P182, P1-55.
2011 Shengmin Sang, Huadong Chen, Ming-Hsiung Pan, Chung S. Yang, Chi-Tang Ho, and Vadimir Badmaev. Bioactive Components in Ginger: Biotransformation and Cancer Preventive Effects. International Conference on Food Factors 2011 (ICoFF 2011), Nov 20-23, 2011. International Convention Center in Taipei, Taiwan, P183, P1-76.
2011 Ching-Shu Lai, You-Syuan Lai, Chi-Tang Ho, and Ming-Hsiung Pan. Magnolol potently suppressed lipopolysaccharide-induced iNOS and COX-2 expression via downregulating MAPK and NF-kB signaling pathways. International Conference on Food Factors 2011 (ICoFF 2011), Nov 20-23, 2011. International Convention Center in Taipei, Taiwan, P184, P1-86.
2011 Chen-yu Tsai, Bonnie Sun Pan, Mei Ling Tsai and Ming-Hsiung Pan. TGF-β-induced fibrogenic responses of hepatic stellate cells and its application to the screening of anti-hepatic fibrosis compounds from Chlorella (Chlorella sp.). International Conference on Food Factors 2011 (ICoFF 2011), Nov 20-23, 2011. International Convention Center in Taipei, Taiwan, P188, P1-173.
2011 Ching-Shu Lai, Vladimir Badmaev, Miguel Jimenez, Chi-Tang Ho and Ming-Hsiung Pan. Xanthigen suppresses adipocyte differentiation through modulation of Sirt1 expression in 3T3-L1 cells. International Conference on Food Factors 2011 (ICoFF 2011), Nov 20-23, 2011. International Convention Center in Taipei, Taiwan, P190, P1-215.
2011 Chieh-Han Chung, Shiming Li, Chi-Tang Ho and Ming-Hsiung Pan. Comparison of the effects of the Tangeretin and 5-hydroxytangeretin in 12-O- Tetradecanoylphorbol-13-acetate-treated human colorectal carcinoma cell. International Conference on Food Factors 2011 (ICoFF 2011), Nov 20-23, 2011. International Convention Center in Taipei, Taiwan, P193, P1-285.
2011 Yi-Shiou Chiou, Yin-Jen Wang, Chi-Tang Ho and Ming-Hsiung Pan. AcEGCG is more potent to prevent DSS-induced colitis than EGCG by activation of the Nrf2-mediated anti-inflammatory signaling. International Conference on Food Factors 2011 (ICoFF 2011), Nov 20-23, 2011. International Convention Center in Taipei, Taiwan, P194, P1-304.
2011 Min-Hau Ho, Mei-Ling Tsai, Chi-Tang Ho and Ming-Hsiung Pan. Inhibitory Effects of Chlorella (Chlorella sp.) Extract on adipogenesis in 3T3-L1 cells. International Conference on Food Factors 2011 (ICoFF 2011) , Nov 20-23, 2011. International Convention Center in Taipei, Taiwan, P199, P1-413.
2011 Min-Hsiung Pan. Inhibitory effect of the urinary metabokites of citrus nobiletin on TPA-induced skin inflammation and tumor promotion in mice. (2011). Cancer Prevention Research and Department of Chemical Biology Ernest Mario School of Pharmacy, Rutgers University, USA. (Invited Lecture).
2011 Min-Hsiung Pan. Inhibitory Effect of Magnolol on TPA-Induced Skin Inflammation and Tumor Promotion in Mice. The 241st ACS National Meeting & Exposition, Mar 27-31, 2011. Anaheim, California, USA. (Oral).
2011 Grace S. Chang, Ching-Shu Lai, Jia-Ching Wu, Chen-Yu Chai, and Ming-Hsuing Pan. Anti-Carcinogenic and Anti-Inflammatory Properties of Nobiletin and 3’4’-didemethylnobiletin. The 241st ACS National Meeting & Exposition, Mar 27-31, 2011. Anaheim, California, USA. (Poster)
2010 Min-Hsiung Pan. Inhibitory effect of the urinary metabolites of citrus nobiletin on phorbol ester-induced skin inflammation and tumor promotion in mice. The 4th AFLAS Congress Meeting, Nov 9-11, 2010. Taipei, Taiwan. OS 12-08, P. 89. (Invited Lecture).
2010 Min-Hsiung Pan. Chemoprevention of colonic tumorigenesis by dietary hydroxylated polymethoxylflavones in azoxymethane-treated mice. International Society for Nutraceuticals and Functional Foods (ISNFF) Conference, Oct 11-15, 2010. Bali, O52, P.11.
2010 Peiju Qiu, Noppawat Charoensinphon, Ryan Riddle, Shiming Li, Min-Hsiung Pan, Chi-Tang Ho, hang Xiao. Novel strategies for cancer chemoprevention using polymethoxylflavones from orange. International Society for Nutraceuticals and Functional Foods (ISNFF) Conference, Oct 11-15, 2010. Bali, O49, P.10.
2010 Chih-Yu Lo, Han-Rong Lin, Shiming Li, Min-Hsiung Pan, Chi-Tang Ho. Trapping of methylglyoxal, a maillard reaction generated bioactive compound, by anthocyanidins in blackcurrent fruit. International Society for Nutraceuticals and Functional Foods (ISNFF) Conference , Oct 11-15, 2010. Bali, O93, P.16.
2010 Min-Hsiung Pan. Pterostilbene inhibits TPA-induced invasion and metastasis of human hepatoma cells through inactivating PKC, MAPK and PI3K/Akt signal transduction pathway. BIT’s 3nd Annual Word Cancer Congress, June 22-25, 2010. Singapore EXPO, Singapore, Track 2-7, p.018.
2010 Lo, Chih-Yu; Chen, Xiu-Yu; Hsuao, Wen Tuan; Li, Shiming; Pan, Min-Hsiung; Ho, Chi-Tang. Trapping of methylglyoxal, a maillard reaction generated bioactive compound, by black current pigments. Abstracts of Papers, 239th ACS National Meeting, Mar 21-25, 2010. San Francisco, CA, United States, ch
2009 Min-Hsiung Pan. Pterostilbene inhibited tumor invasion via suppressing multiple signal transduction pathways in human hepatocullular carcinoma cells. ISNFF 2009, Oct 31-Nov 4, 2009. San Francisco. CA. O79, p.80.
2009 Lee, Jonghun; Lai, Ching-Shu; Pan, Min-Hsiung; Ho, Chi-Tang.Anti-inflammatory activity of rosmanol transformed from carnosol of rosemary. Abstracts of Papers, 238th ACS National Meeting, Aug 16-20, 2009. Washington, DC.
2009 Lo, Chih-Yu; Li, Shiming; Kuo, Yu-Ching; Pan, Min-Hsiung; Ho, Chi-Tang. Trapping of methylglyoxal, a Maillard reaction generated bioactive compound, by hydroxybenzene derivatives. Abstracts of Papers, 238th ACS National Meeting, Aug 16-20, 2009. Washington, DC.
2009 Sang, Shengmin; Pan, Min-Hsiung; Hong, Jungil; Wu. Hou; Shao, Xi; Yang, Chung S.; Ho, Chi-Tang. Impact of process on the chemical profile and anti-inflammatory and anticancer activities of ginger. Abstracts of Papers, 238th ACS National Meeting, Aug 16-20, 2009. Washington, DC.
2009 Min-Hsiung Pan*, Ching-Shu Lai, Ying-Jan Wang, Shiming Li, Chi-Tang Ho. 3',4'-didemethylnobiletin inhibits 12-O-tetradecanoylphorbol-13-acetate – induced acute inflammation and two-stage mouse skin carcinogenesis by blocking the expression of ornithine decarboxylase, inducible nitric oxide synthase and cyclooxygenase-2. 12th International Flavor Conference and the 4th George Charalambous Memorial Symposium, May 25-29, 2009. Island of Skiathos, Greece, p27, O-III-04. (Oral presentation).
2009 Ying-Jan Wang, Ming-Chen Yang and Ming-Hsiung Pan. Dihydrolipoic Acid Inhibits Tetrachlorohydroquinone-Induced TumorPromotion through prevention of Oxidative Damage.12th International Flavor Conference and the 4th George Charalambous Memorial Symposium, May 25-29, 2009. Island of Skiathos, Greece, p27, O-III-02.
2009 Ching-Shu Lai, Ying-Jan Wang, Jonghun Lee, Chi-Tang Ho, and Min-Hsiung Pan. Rosmanol suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 through down-regulating nuclear factor-kB pathway in murine macrophages. 12th International Flavor Conference and the 4th George Charalambous Memorial Symposium, May 25-29, 2009. Island of Skiathos, Greece, p19, P-31.
2009 Sheng-Yow Ho, You-Syuan Lai, Hou Wu, Chi-Tang Ho, and Min-Hsiung Pan. Anti-inflammatory effect of magnolol through suppressed lipopolysaccharide- induced expression of iNOS and COX-2 in murine macrophages. 12th International Flavor Conference and the 4th George Charalambous Memorial Symposium, May 25-29, 2009. Island of Skiathos, Greece, p20, P-33.
2009 Yu-Ching Kuo, Ching-Shu Lai, Chi-Tang Ho, and Min-Hsiung Pan. Diffeential inhibitory effects of inotilone on inflammatory mediator, iNOS and COX-2, in LPS-stimulated murine macrophage. 12th International Flavor Conference and the 4th George Charalambous Memorial Symposium , May 25-29, 2009. Island of Skiathos, Greece, p20, P-34.
2009 Lo, Chih-Yu; Pan, Min-Hsiung; Li, Shiming; Ho, Chi-Tang. Determination of   dibenzoylmethane and reactive metabolites by liquid chromatography and linear ion trap mass spectrometry. 12th International Flavor Conference and the 4th George Charalambous Memorial Symposium, May 25-29, 2009. Island of Skiathos, Greece.
2009 Yi-Shiou Chiou, Chi-Tang Ho, Min-Hsiung Pan*. Pterostilbene, an active constituent of blueberries, suppresses aberrant crypt foci and tumor formation in azoxymethane-induced colon carcinogenesis model in mice. Proceedings of 24th Joint Annual Conference of Biomedical Sciences, Mar 21-22, 2009. NDMC, Taipei: P584, pp297.
  1. Pan, Min-Hsiung; Lai, Ching-Shu; Wu, Jia-Ching, and Ho, Chi-Tang. Effect of Flavonoids from Fruits and Vegetables in the Prevention and Treatment of Cancer. In Cancer Chemoprevention and Treatment by Diet Therapy, Edited by William C.S. Cho., Springer, 2013, Chapter 2, pp. 23-54.

  2. Bai, Naisheng; He, Kan; Roller, Marc; Lai, Ching-Shu; Shao, Xi; Pan, Min-Hsiung; Ho, Chi-Tang. Secoiridoid glucosides from Fraxinus excelsior with effects on LPS-induced nitrite production in RAW 264.7 macrophage and human cancer cell lines. In African Natural Plant Products Volume II: Discoveries and Challenges in Chemistry, Health and Nutrition, ACS Symposium Series 1127, Edited by H. Rodolfo Juliani, James E. Simon and Chi-Tang Ho, American Chemical Society, Washington DC., 2013, pp. 115-126.

  3. Chiou, Yi-Shiou; Ma, Nianhan Jia-Lin; Sang, Shengmin; Li, Shiming; Wang, Ying-Jan; Ho, Chi-Tang; Pan, Min-Hsiung*. Peracetylated epigallocatechin-3-gallate, as an epigallocatechin-3-gallate prodrug, potently prevents human breast cancer cell metastasis by targeting the matrix metalloproteinases activity and fatty acid synthase expression. In Nutrition, Functional and Sensory Properties of Foods, Edited by Chi-Tang Ho, Cynthia Mussinan, Fereidoon Shahidi and Ellene Tratras Contis, Royal Society of Chemistry, Cambridge, UK, 2013, pp. 291-302.

  4. Lai, Ching-Shu; Zeng, Jun-Yan; Li, Shiming; Huang, Qingrong; Ho, Chi-Tang; Pan, Min-Hsiung*. Inhibitory effects 5-demethyltangeretinand 5-acetyloxy-6,7,8,4'-tetramethoxyflavone on human colon cancer cells. In Nutrition, Functional and Sensory Properties of Foods, Edited by Chi-Tang Ho, Cynthia Mussinan, Fereidoon Shahidi and Ellene Tratras Contis, Royal Society of Chemistry, Cambridge, UK, 2013, pp. 281-290.

  5. Lai, Ching-Shu; Chang, Grace S.; Li, Shiming; Lo, Chih-Yu; Ho, Chi-Tang; Pan, Min-Hsiung*. Comparison of anti-proliferative and anti-inflammatory effects of nobiletin and its urinary metabolite, 3′,4′-didemethylnobiletin. In Nutrition, Functional and Sensory Properties of Foods, Edited by Chi-Tang Ho, Cynthia Mussinan, Fereidoon Shahidi and Ellene Tratras Contis, Royal Society of Chemistry, Cambridge, UK, 2013, pp. 269-280.

  6. Ho, Chi-Tang; Pan, Min-Hsiung; Ho, Yuan-Soon. The molecular targets of garcinol confer antitumor effects. In Nutrition, Functional and Sensory Properties of Foods, Edited by Chi-Tang Ho, Cynthia Mussinan, Fereidoon Shahidi and Ellene Tratras Contis, Royal Society of Chemistry, Cambridge, UK, 2013, pp. 251-255.

  7. Wu, Jia-Ching; Lai, Ching-Shu; Dushenkov, Slavik; Wang, Ying-Jan; Ho, Chi-Tang; Pan, Min-Hsiung*. Impact on epigenetics in cancerchemprevention by natural dietary compounds. In Nutrition, Functional and Sensory Properties of Foods, Edited by Chi-Tang Ho, Cynthia Mussinan, Fereidoon Shahidi and Ellene Tratras Contis, Royal Society of Chemistry, Cambridge, UK, 2013, pp. 243-250.

  8. Ho, Yuan-Soon; Pan, Min-Hsiung. Tea extracts confer its antiproliferating effects through inhibition of nicotine- and estrogen-induced 9-nicotinic acetylcholine receptor upregulation in human breast cancer cells. In Nutrition, Functional and Sensory Properties of Foods, Edited by Chi-Tang Ho, Cynthia Mussinan, Fereidoon Shahidi and Ellene Tratras Contis, Royal Society of Chemistry, Cambridge, UK, 2013, pp. 257-268.

  9. Pan, Min-Hsiung; Lia, Ching-Shu; Kuo Yu-Ching and Ho Chi-Tang. Comparative studies on biological activity of inotilone andmethylinotilone from Inonotus Species. In Recent Advances in Food and Flavor Chemistry: Food Flavor and Encapsulation, Health Benefits, Analytical Methods, and Molecular Biology of Functional Foods. Edited by Ho, C.-T.; Mussinan C. J.; Shahidi F. and Tratras Contis E. Royal Society of Chemistry, Cambridge, UK, 2010, page 448-456.

  10. Wenping Tang, Min-Hsiung Pan, Shiming Li and Chi-Tang Ho. Garcinol from Garcinia indica: Chemistry and Health Beneficial Effects. In Tropical and Subtropical Fruits: Flavors, Color, and Health Benefits, 2011, pp 133–145

  11. Min-Hsiung Pan and Wei-Jen Chen. The cancer preventive potential of tea polyphenol EGCG in HER2-positive breast cancer. Functional Foods. ACS Books. Edited by Takayuki Shibamoto, Kazuki kanazawa, Fereidoon Shahidi and Ho, C, T. ACS Symposium Series 993, 2008, Chapter 28, pp335-344, American Chemical Society.

  12. Min-Hsiung Pan*, Hui-Jun Kang, Wei-Jen Chen, Chih-Yu Lo, Shiming Li, Shengmin Sang, and Chi-Tang Ho. Induction of apoptosis by acetylated black tea polyphenol through reactive oxygen species production, cytochrome c release, and caspases activation in human leukemia HL-60 cells. ACS Books. Edited by Takayuki Shibamoto, Kazuki kanazawa, Fereidoon Shahidi and Ho, C, T. ACS Symposium Series 993, 2008, Chapter 29, pp345-361, American Chemical Society.

计画名称 执行期限 补助或委讬机构 执行情形
研究Pterostilbene与其类似物经调节生理时钟和肠道菌群对改善代谢异常及预防肠癌形成之分子机转 2020/08/01~2023/07/31 科技部 执行中
探讨5-去甲基川陈皮素预防B[a]P/DSS诱导肠癌进展与肠道菌相变化之相关分子机制 2019/08/01~2022/07/31 科技部 执行中
以体内外模式评估高登氧补给液之保健功效 2020/11/05~2021/05/30 群宝基因科技有限公司 执行中
台湾杂粮作物萃取物对减缓高脂及果糖饮食诱导小鼠非酒精性脂肪肝及高血糖之功效 2020/01/01~2020/12/31 农委会农粮署 已结案
探讨乌龙茶萃取物对于脂肪堆积与肠道菌相之功效 2020/03/18~2020/11/30 农委会茶业改良场 已结案
探讨人参对于细悬浮微粒诱发肺脏发炎之保护功效及其相关机制研究 2019/06/01~2020/05/31 科技部 已结案
探讨藻类加工产品对高龄者肠道菌相及生理代谢的改善 2018/05/01~2020/09/30 科技部 已结案
桑叶调控脂肪代谢研究计画 2019/04/20~2019/12/31 财团法人台湾区蚕业发展基金会 已结案
红豆水萃物调节高脂饮食诱导之肝脏脂肪代谢及降低非酒精性脂肪肝 2019/01/01~2019/12/31 农委会农粮署 已结案
益生菌抗癌功效之检测 2018/07/01~2018/12/31 生展生物科技股份有限公司 已结案
Stilbenoids 化合物抑制高脂饮食诱导肥胖促进之溃疡性肠癌发展的化学预防功效与机制研究 2016/08/01~2019/07/31 科技部 已结案
5-羟基多甲氧基黄酮抑制benzo[a]pyrene 诱导致癌之化学预防功效与分子机转探讨 2016/08/01~2019/07/31 科技部 已结案
建立台湾杂粮作物之功能性鑑定平台与保健饮品开发 2018/01/01~2018/12/31 农委会农粮署 已结案
柑橘幼果皮中不同化学组成之多甲氧基类黄酮polymethoxyflvones(PMFs)对减缓高脂饮食诱导小鼠肥胖之功效研究计画书 2017/04/01~2018/03/31 大江生医股份有限公司 已结案
探讨红豆萃取物的抗肥胖分子机制与肠道菌相之影响 2017/01/01~2017/12/31 农委会农粮署 已结案
红豆萃取物降低肥胖之功效与低糖益生菌养生片开发 2016/01/01~2016/12/31 农委会农粮署 已结案
昭和草预防及治疗肝纤维化功效之评估研究计画 2016/02/01~2017/01/31 绿茵生技股份有限公司 已结案
Theasinensins标准品制备与定量方法建立 2016/04/14~2016/12/31 农委会茶业改良场 已结案
倒捻子有效成分分析及功能性评估 2016/10/01~2017/04/30 东洋生技股份有限公司 已结案
以Epigenetic为标的探讨Stilbenoids化合物抑制结肠直肠癌之化学预防功效与机制研究 2013/08/01~2016/07/31 科技部 已结案
羟基多甲氧基类黄酮(hydroxyl polymethoxyflavones)抑制发炎相关疾病之化学预防功效与机制探讨 2012/08/01~2016/07/31 科技部 已结案
计画期间
  1. Hsu, Ping-Chi; Pan, Min-Hsiung; Jiang, Yi-Peng; Chen, Meng-Ting. Herbal natural complex for improving sperm function and manufacturing method thereof. Patent Number: CN 201636012.

  2. Badmaev, Vladimir; Pan, Min-Hsiung . Method Use of Polymethoxyflavones (PMFs) in Body Composition Management. US Patent. 20,160,082,066: 2016.

  3. Ho, Chi-Tang; Li, S.; Pan, Min-Hsiung; Lo, Chih-Yu; Dushendov, Slavik. Provided herein are compositions enriched in polyhydroxylated polymethoxyflavones useful as dietary supplements, food additives, pharmaceutical compositions, nutraceutical compositions and cosmetic compositions. Patent Number: WO/2007/109071

  4. Pan, Min-Hsiung; Chang, Chi-I; Wu, Chia-Li; Hsu, Pang-Kuei. Trans-2-nonadecyl-4-hydroxymethyl-1,3-dioxolane and method for producing thereof. Patent Number: CN 201529564

  5. Pan, Min-Hsiung and Wu, Chia-Li. The uses of hydroxyl polymethoxylflavones and/or derivative thereof. Patent Number: CN 201507725

  6. Liu, Chen-Shan; Pan, Min-Hsiung; Chang, Chih-I. The extraction method of orchid extracts and its application. Patent Number: CN 201318647

  7. Tu, Shih-Hsin; Ku, Chung-Yu; Chen, Ching-Shyang; Huang, Ching-Shui; Lee, Chia-Hwa; Chen, Li-Ching; Pan, Min-Hsiung; Chang, Hui-Wen; Chang, Chien-Hsi; Chang, Yu-Jia; Wei, Po-Li; Wu, Chih-Hsiung; Ho, Yuan-Soon. Use of tea polyphenols for treating and/or preventing nicotine or nicotine-derived compounds or estrogen induced breast cancer. Patent Number: CN 201233385

  8. Pan, Min-Hsiung; Tsai Chen-Yu; Chang, Chih-I; Sun, Bonnie. Clam purification processes and purification of substance. Patent Number: CN 201114465

研究方向

癌症化学预防(cancer chemoprevention)即以天然或合成之化合物预防、抑制、延缓或逆转癌症的形成与发展,亦成为目前预防癌症与疾病形成的重要策略。本实验室之研究方向主要以细胞模式与动物模式评估与探讨饮食中天然物活性成分,包括薑黄(curcumin)、柑橘果皮(多甲氧基类黄酮;PMFs)、薑 (gingerols与 shogaols) 、蓝莓 (pterostilbene与 stilbenes) 、茶(catechins and EGCG)与养殖贝类文蛤、蚬之抗发炎、抗癌、抗肝纤维化、抗转移与癌症化学预防等生理活性与分子机制;基于食品保健与疾病预防的角度,我们希望借由提供饮食中天然物的癌症化学预防活性与科学证据,以达到维护国人身体健康与降低癌症等疾病的发生。

研究技术

细胞模式 (In Vitro)

  1. 诱发人类癌细胞凋亡(apoptosis)与自体吞噬(autophagy)

  2. 诱发人类癌细胞周期停滞(cell cycle arrest)

  3. 抑制癌细胞转移(migration)与侵入(invasion)

  4. 抑制LPS诱发巨噬细胞(RAW 264.7)发炎反应

  5. 抑制TGF-b诱发星状细胞(HSC-T6)活化

动物模式 (In Vivo)

  1. 小鼠皮肤二阶段致癌模式(DMBA/TPA)

  2. 化学物质(AOM与DSS)致肠癌模式

  3. 化学物质(CCl4与DMN)诱发大鼠肝纤维化模式

  4. 高脂饮食肥胖模式及肠道菌相探讨

  5. 老化鼠动物模式

  6. 免疫缺乏小鼠肺转移(lung metastasis)模式

  7. ​Xenograft 模式

1996/09-2000/06 国立台湾大学医学院生化学研究所博士

1993/09-1995/06 国立台湾海洋大学食品科学研究所硕士

1991/09-1993/06 国立台湾海洋大学水产食品科学系学士

 

2018/08~              国立台湾大学食品科学所 特聘教授兼所长

2015/08-2018/07 国立台湾大学食品科学所 特聘教授

2013/08-2015/07 国立台湾大学食品科学所 教授

2012/08-2013/07 国立高雄海洋科技大学水产食品科学系 教授兼研发处研发长

2011/08-2012/07 国立高雄海洋科技大学水产食品科学系 教授兼教务处副教务长

2009/07-2011/01 国立高雄海洋科技大学水产食品科学系
                               教授兼实习就业暨校友服务中心主任

2007/08-2008/07 国立高雄海洋科技大学水产食品科学系 教授兼系主任

2005/08-2007/07 国立高雄海洋科技大学水产食品科学系 副教授兼系主任

2005/06-2005/09 美国罗格斯大学食品科学系 访问学者

2004/08-2007/07 国立高雄海洋科技大学水产食品科学系 学副教授

2001/08-2004/07 国立高雄海洋技术学院水产食品科学系 助理教授

2000/08-2001/07 台大医学院生化学研究所 博士后研究员

1995/07-1996/06 台大医院肿瘤医学部 研究助理

Editor-in-Chief:
Current Research in Nutrition and Food Science (2017/10/03~now)
Associate Editor:
Journal of Food and Drug Analysis (2013~now)
Editorial Board:
Food Science and Human Wellness,
Journal of Functional Foods,
Journal of Traditional and Complementary Medicine,
World Journal of Gastroenterology, World Journal of Pharmacology
Journal Reviewer:
Biochemical Pharmacology,
BioMed Complementary and Alternative Medicine,
Cancer Chemotherapy and Pharmacology,
Cancer Letters, Cancer Prevention Research,
Cancer Research, Carcinogenesis, Cytokine,
Evidence Based Complementary and Alternative Medicine,
Food Chemical and Toxicology, Food Chemistry,
Food & Function, Immunopharmacology,
International, Journal Agriculture and Food Chemistry,
Journal of Cancer Molecules, Journal of Food Science, 
Journal of Food and Drug Analysis, Journal of Food Biochemistry,
Journal of Functional Foods, Medical Oncology,
Molecular Biology Reports, Molecular,
Nutrition and Food Research, Oncotarget,
Pharmacological Research, PLOS ONE, PROTEOMICS,
Scientific Reports, Telethon, The Journal of Urology
  • 2020 台湾农业化学会学术荣誉奖 Taiwan Academic Achievement Award of Agricultural Chemical Society of Taiwan (2020)
  • 2020 董大成博士癌症基础医学研究杰出奖 Dr. Tung Ta-Cheng’s Basic Cancer Research Award (2020)
  • 科技部107年度杰出研究奖 MOST Outstanding Research Award (2018)
  • 2018科睿唯安全球高被引学者Highly Cited Researchers of Clarivate Analytics (2018)
  • 2018 保健食品学会杰出学术奖 Health Food Society Outstanding Academic Award (2018)
  • 2018 年度台湾食品科学技术学会杰出研究奖 Outstanding Research Award of Taiwan Association for Food Science and Technology (2018)
  • 2018 国际期刊农业暨食品化学杂志(JAFC)杰出审查奖 Journal of Agricultural and Food Chemistry (JAFC) Excellence in Review Award (2018)
  • 2015 国际期刊农业暨食品化学杂志(JAFC)杰出审查奖Outstanding reviewer Award of Journal of Agriculture and Food Chemistry (2015)
  • 担任国立台湾大学食安中心外部食品专家National Taiwan University, Food Safety Center, Health and safety Visit External experts. (2015-2016)
  • 行政院国科会优秀年轻学者研究计画 (2012-2015)
  • 美国化学学会农业化学暨食品化学组会士Fellow, Agricultural & Food Chemistry Division, American Chemistry Society (2014)
  • 台湾保健食品学会 杰出学术研究暨技术开发奖Outstanding Research and Technology Development Award of Health Food Society of Taiwan (2013)
  • 教育部特殊优秀人才奖励(2010-2012)
  • 行政院国科会100年度杰出研究奖Outstanding Research Award of National Science Council (2011)
  • 国立高雄海洋科技大学98学年度卓越研究奖Outstanding Research Award of National Kaohsiung Marine University, Taiwan (2009)
  • 荣获中华民国第46届十大杰出青年The 46th Ten Outstanding Young People, Taiwan (2008)
  • 行政院国科会吴大猷先生纪念奖 Ta-You Wu Memorial Award of National Science Council, Taiwan (2007)