| Professor | |
| Job Title | Professor |
| Name | Shu-Chen Hsieh |
| Office Tel No. | 02-3366-9871 |
| scjhsieh@ntu.edu.tw | |
| Education | Ph.D, Institute of Biochemistry & Molecular Biology, National Yang-Ming University Masters, Institute of Biochemistry & Molecular Biology, National Yang-Ming University BMV, Department of Veterinary Medicine, National Taiwan University |
| Research Expertise | Molecular Biology, Health Foods, Chronic Disease Prevention |
| Personal Website | http://www2.fst.ntu.edu.tw/teacher/hsieh/teacher-hsieh.htm |
| 2022 | Chung, C.; Chao, T.Y.; Chen, H.J.; Xie, G.R.; Chiang, W.; Hsieh, S.C. (2022, Feb). Investigating the Impact of Extruded Dehulled Adlay with Specific In Vitro Digestion Properties on Blood Lipids in Subjects with Mild to Moderate Dyslipidemia. Foods, 11, 493-506. |
| 2021 | Wang, H.C.; Wang, C.S.; Hsieh, S.C.; Hung, Y.T.; Chen, H.H. (2021,Nov). Evaluation of a new-formula shampoo containing 6% glycyrrhetinic acid complex for scalp seborrheic dermatitis: A pilot study. Journal of Cosmetic Dermatology. |
| 2021 | Hsu, P.H.; Chen, W.H.; Lu, C.J.; Hsieh, S.C.; Lin, S.C.; Mai, R.T.; Chen, S.Y. (2021, SEP). Hesperidin and chlorogenic acid synergestically inhibit the growth of breast cancer cells via estrogen receptor/mitochondrial pathway. Life, 11, 950. |
| 2021 | Chao, T.Y.; Hsieh, C.C.; Kuo, Y.H.; Wan, C.H.; Hsieh S.C. (2021, May). Bracteanolide A abrogates oxidative stress-induced cllular damage and protects against hepatic ischemia and reperfusion injury in rats. Food Science & Nutrition, 9, 4758-4769. |
| 2021 | Chao, T.Y.; Hsieh, C.C.; Hsu, S.M.; Wan, C.H.; Lian, G.T.; Tseng, Y.H.; Kuo, Y.H.; Hsieh S.C. (2021, Mar). Ergostatrien-3-beta-ol (EK100) from Antrodia camphorata attenuates stress, inflammation, and liver injury in viitro and in vivo. Preventive Nutrition and Food Science, 26 (1)1-9 |
| 2020 | Yeh, Y.T.; Lu, T.J.; Lian, G.T.; Lung, M.C.; Lee, Y.L.; Chiang, A.N.; Hsieh S.C. (2020, Mar). Chinese olive (Canarium album L.) fruit regulates glucose utilization by activating AMP-activated protein kinase. The FASEB journal, 34(6), 7866-7884. |
| 2020 | Chu, K.V.; Fan, C.S.; Chen, C.C.; Hsieh, S.C.; Huang, T.S. (2020, Jan). Octyl gallate induces pancreatic ductal adenocarcinoma cell apoptosis and suppresses endothelial-mesenchymal transition-promoted M2-macrophages, HSP90 secretion and tumor growth. Cells, 9(1), 91. |
| 2020 | Chang W.C.; Hu, Y.T.; Huang, Q.; Hsieh S.C.; Ting,Y, (2020, Jan). Development of a topical applied functional food formulation: Adlay bran oil nanoemulgel. LWT-Food Science and Technology, 117, 108619. |
| 2019 | Tseng, Y.H.; Hsieh, C.C.; Kuo, T.Y.; Liu, J.R.; Hsu, T.Y.; Hsieh S.C. (2019, Dec). Construction of a Lactobacillus plantarum Strain Expressing the Capsid Protein of Porcine Circovirus Type 2d (PCV2d) as an Oral Vaccine. Indian Journal of Microbiology, 59(4), 490-499. |
| 2019 | Kuo, Y.H.; Yeh, Y.T.; Pan, S.H.; Hsieh, S.C. (2019, Sep). Identification and SAtructural Elucidation of Anti-Inflammatory Compounds from Chinese Olive (Canarium Album L.) Fruit Extracts. Foods, 8(10), 441-454 |
| 2019 | Ting, Y.; Hu, Y.T.; Hu J.Y.; Chang, W.C.; Huang, Q.; Hsieh, S.C. (2019,Sep). Nano-Emulsified Adlay Bran Oil Reduces Tyrosinase Activity and Melanin Synthesis in B16F10 Cells and Zebrafish. Food Science and Nutition, 7(10), 3216-3223 |
| 2019 | Tseng, Y. H.; Chang, C. W.; Chiang, W. C.; Hsieh, S. C. (2019, Jan). Adlay bran oil suppresses hepatic gluconeogenesis and attenuates hyperlipidemia in type 2 diabetes rats. Journal of Medicinal Food, 22(1), 22-28. |
| 2018 | Kao, Y. U.; Yeh, Y. T.; Chiang, A. N.; Hsieh, S. C. (2018, May). Mechanisms Underlying the Preventive Effects of Canarium album L. ethanol Extract on Modulation of Hyperglycemia and Hypercholesterolemia in Diabetic Rats. Journal of Food and Nutrition Research, 6(4), 261-270. |
| 2018 | Kao, Y. U.; Yeh, Y. T.; Chiang, A. N.; Hsieh, S. C. (2018, May). Study on Mechanisms Underlying the Preventive Effects of Canarium album L. ethanol Extract on Modulation of Hyperglycemia and Hypercholesterolemia in Diabetic Rats. Journal of Food and Nutrition Research, 6(4), 261-270. |
| 2018 | Yeh, Y. T.; Cho, Y. Y.; Hsieh, S. C.; Chiang, A. N. (2018, Jan). Chinese olive extract ameliorates hepatic lipid accumulation in vitro and in vivo by regulating lipid metabolism. Scientific Reports, 8(1), 1057-1069. |
| 2017 | Wang, H. C.; Chu, Y. L.; Hsieh, S. C.; Sheen, L. Y. (2017, Nov). Diallyl trisulfide inhibits cell migration and invasion of human melanoma a375 cells via inhibiting integrin/facal adhesion kinase pathway.. Environmental Toxicology, 32(11), 2352-2359. |
| 2017 | Yeh, Y. T.; Chiang, A. N.; Hsieh S. C. (2017, Oct). Chinese Olive (Canarium album L.) Fruit Extract Attenuates Metabolic Dysfunction in Diabetic Rats. Nutrients, 9(10), 1123-1140. |
| 2017 | Hu, Y. T.; Ting, Y.; Hu, J. Y.; Hsieh, S. C. (2017, Jan). Techniques and methods to study functional characteristics of emulsion systems. Journal of Food and Drug Analysis, 25(1), 16-26. |
| 2016 | Hsieh, S. C.; Hsieh, W. J.; Chiang, A. N.; Su, N. W.; Yeha, Y. T.; Liao, Y. C. (2016, Dec). The methanol-ethyl acetate partitioned fraction from Chinese olive fruits inhibits cancer cell proliferation and tumor growth by promoting apoptosis through the suppression of the NF-κB signaling pathway. Food & Function, 7(12), 4797-4803. |
| 2016 | Hsiao, Y. W.; Lai, T.C.; Lin, Y. H.; Su, C. Y., Lee, J. J.; Liao, A. T.; Lin, Y. F.; Hsieh, S. C.; Wu, A. T. H.; Hsiao, M. (2016, Aug). Granulysin expressed in a humanized mouse model induces apoptotic cell death and suppresses tumorigenicity. Oncotarget, doi: 10.18632/oncotarget.11473. |
| 2016 | Hsieh, C. C.; Liao, C. C.; Liao, Y. C.; Hwang, L. S.; Wu, L. Y.; Hsieh, S. C. (2016, Jun). Proteomic changes associated with metabolic syndrome in a fructose-fed rat model. Journal of Food and Drug Analysis, 24 (4), 754-761. |
| 2016 | Hsieh, S. C.; Liu, J. M.; Pua, X. H.; Ting, Y.; Hsu, R. J.; Cheng, K. C. (2016, Mar). Optimization of Lactobacillus acidophilus cultivation using taro waste and evaluation of its biological activity. Appl Microb Biotechnol, 100(6), 2629-2639. |
| 2015 | Chiang, H. H.; Chen, K. I.; Liu, C. T.; Hsieh, S. C.; Cheng, K. C. (2015, Nov). Soymilk Isoflavone Conversion Prediction by Adaptive Neuro-Fuzzy Inference System. Transactions of the ASABE, 58(6), 1853-1860. |
| 2015 | Hsieh, C.C.; Hsu, S. M.; Hwang, L. S.; Chiu, J. C.; Lu, W. C.; Wu, Y. L.; Hsieh, S. C. (2015, Apr). Protective effects of the extract from longan flower against hepatic ischemia/reperfusion injury in rats. Journal of functional foods, 12, 570-579. |
| 2015 | Huang, C. Y.; Chen, W. M.; Tsay, Y. G.; Hsieh, S. C.; Lin, Y.; Lee, W. J., Sheu, W. H.; Chiang, A. N. (2015, Feb). Differential regulation of protein expression in response to polyunsaturated fatty acids in the liver of apoE-knockout mice and in HepG2 cells. Journal of Biomedical Science, 22,12. |
| 2014 | Lin, S. H., Chen, W. C., Lu, K. H., Chen, P. J., Hsieh, S. C., Pan, T. M., Chen, S.T., Sheen, L.Y. (2014, Oct). Down-regulation of Slit-Robo pathway mediating neuronal cytoskeletal remodeling processes facilitates the antidepressive-like activity of Gastrodia elata Blume. Jouranl of Agriculture and Food Chemistry, 29;62(43):10493-503. |
| 2014 | Lin, S. P.; Hsieh, S. C.; Chen, K. I.; Demirci, A.; Cheng, K. C. (2014, Feb). Semi-continuous bacterial cellulose production in a rotating disk bioreactor and its materials properties analysis. Cellulose, 21, 835-844. |
| 2014 | Hsieh, C. C.; Hsieh, S. C.; Chiud, J. H.; Wu, Y. L. (2014, Feb). Protective effects of N-acetylcysteine and a Prostaglandin E1 analogue, Alprostadil, against Hepatic Ischemia–Reperfusion Injury in Rats. Journal of Traditional and Complementary Medicine, 4, 64-71. |
| 2014 | Wang, C. H.; Hsieh, S. C.; Wang, H. J.; Chen, M. L.; Lin, B. F.; Chiang, B. H.; Lu, T. J. (2014, Feb). Concentration Variation and Molecular Characteristics of Soluble (1,3;1,6)-beta-d-Glucans in Submerged Cultivation Products of Ganoderma lucidum Mycelium. Journal of agricultural and food chemistry, 62, 634-641. |
| 2014 | Hsieh, C. C.; Hsieh, S. C.; Chiu, J. H.; Wu, Y. L. (2014, Jan). Preconditioning somatothermal stimulation on Qimen (LR14) reduces hepatic ischemia/reperfusion injury in rats. BMC Complementary and Alternative Medicine, 14, 18. |
| 2014 | Weerawatanakorn, M.; Hsieh, S. C.; Tsai, M. L.; Lai, C. S.; Wu, L. M.; Badmaev, V.; Ho, C. T.; Pan, M. H. (2014, Jan). Inhibitory effect of tetrahydrocurcumin on dimethylnitrosamine-induced liver fibrosis in rats. Journal of Functional Foods , 7, 305-313.（本人為第一作者） |
| 2013 | Hsieh, S. C.; Kuo, S. N.; Zheng, Y. H.; Tsai, M. H.; Lin, Y. S.; Lin, J. H. (2013, Dec). The E3 Ubiquitin Ligase SIAH2 Is a Prosurvival Factor Overexpressed in Oral Cancer. ANTICANCER RESEARCH, 33, 4965-4974. |
| 2013 | Wang, C. H.; Lin, J. H.; Lu, T. J.; Chiang, A. N.; Chiou, S. T.; Chen, Y. A.; Pan, M. H.; Hsieh, S. C. (2013, Dec). Establishment of Reporter Platforms Capable of Detecting NF-κB Mediated Immuno-Modulatory Activity. Journal of Agricultural and Food Chemistry, 61: 12582-12587. |
| 2013 | Chang, Y. C.; Tsai, M. H.; Sheu, W. H.; Hsieh, S. C.; Chiang, A. N. (2013, Nov). The therapeutic potential and mechanisms of action of quercetin in relation to lipopolysaccharide-induced sepsis in vitro and in vivo. Plos One, 8 (11), e80744. |
| 2013 | Hsu, C. H.; Ho, Y. S.; Lai, C. S.; Hsieh, S. C.; Chen, L. H.; Lin, E.; Ho, C. T.; Pan, M. H. (2013, Nov). Hexahydro-β-Acids Potently Inhibit 12‑O‑Tetradecanoylphorbol 13-Acetate-Induced Skin Inflammation and Tumor Promotion in Mice. Journal of Agricultural and Food Chemistry, 61: 11541-11549. |
| 2013 | Lin, J. H.; Hsieh, S. C.; Chen, J. N.; Tsai, M. H.; Chang, C. C. (2013, Aug). WWP1 gene is a potential molecular target of human oral cancer. Oral surgery, oral medicine, oral pathology and oral radiology, 116(2), 221-231. |
| 2013 | Lai, L. R.; Hsieh, S. C.; Huang, H. Y.; Chou, C. C. (2013, May). Effect of lactic fermentation on the total phenolic, saponin and physic acid contents as well as anti-colon cancer cell proliferation activity of soymilk. Journal of Bioscience and Bioengineering, 115(5), 552-556. （本人為第一作者） |
| 2013 | Lin, M. H.; Tsai, T. Y.; Hsieh, S. C.; Yu, R. C.; Chou, C. C. (2013, May). Susceptibility of Vibrio parahaemolyticus to disinfectants after prior exposure to sublethal stress. Food Microbiology, 34, 202-206. (SCI). |
| 2013 | Wang, T. M.; Hsieh, S. C.; Chen, J. W.; Chiang, A. N. (2013, May). Docosahexaenoic acid and eicosapentaenoic acid reduce C-reactive protein expression and STAT3 activation in IL-6-treated HepG2 cells. Molecular and Cellular Biochemistry, 377, 97-106. |
| 2013 | Wang, K. W.; Chueh, L. L.; Wang, M. H.; Huang, Y. T.; Fang, B. H.; Chang, C. Y.; Fang, M. C.; Chou, J. Y.; Hsieh, S. C.; Wan, C. H. (2013, Apr). Multiplex polymerase chain reaction assay for the detection of minute virus of mice and mouse parvovirus infections in laboratory mice. Laboratory Animals, 47(2), 116-121. |
| 2012 | Wang, M. E.; Chen, Y. C.; Chen, I. S.; Hsieh, S. C.; Chen, S. S.; Chiu, C. H. (2012, Oct). Curcumin protects against thioacetamide-induced hepatic fibrosis by attenuating the inflammatory response and inducing apoptosis of damaged hepatocytes. Journal of Nritritional Biiochemistry, 23, 1352-1366. (SCI). |
| 2012 | Wang, H. C.; Hsieh, S. C.; Yang, J. H.; Lin, S. Y.; Sheen, L. Y. (2012, Apr). Diallyl trisulfide induces apoptosis of human basal cell carcinoma cells via endoplasmic reticulum stress and the mitochondrial pathway. Nutrition and cancer, 64(5), 770–780. (SCI). |
| 2012 | Hsieh, W. J.; Chiou, S. T.; Pan, M. H.; Hsieh, S. C. (2012, Jan). Establishment and evaluation of biotechnological platform for screening health food with anti-inflammation ability. J Tradit Complement Med, 2, p76-80. |
| 2011 | Wang, T. M.; Chen, C. J.; Lee, T. S.; Chao, H. Y.; Wu, W. H.; Hsieh, S. C.; Sheu, H. H.; Chiang, A. N. (2011, Feb). Docosahexaenoic acid attenuates VCAM-1 expression and NF-κB activation in. Journal of Nutritional Biochemistry, (22) 187–194. (SCI). |
| 2010 | Lin, K.L., Chou, C.H., Hsieh, S.C., Hwa, S.Y., Lee, M.T., and Wang, F.F. (2010, Nov). Transcriptional upregulation of DDR2 by ATF4 facilitates osteoblastic differentiation through p38 MAPK-mediated Runx2 activation. Journal of Bone and Mineral Research, 25, 2489-2503. (SCI). |
| 2009 | Wang, H.C., Yang, J.H., Hsieh, S.C., and Sheen, L.Y. (2010, Jun). Allyl Sulfides Inhibit Cell Growth of Skin Cancer Cells through. Journal of Agriculture and Food Chemistry, 58, 7096-7103. (SCI). |
| 2009 | Hsieh, S. C.; Chen, N. T.; Lo, S. H. (2009, Jun). Conditional loss of PTEN leads to skeletal abnormalities and tumor formation. Mol. Carcinog. MOLECULAR CARCINOGENESIS, 48:545–552. (SCI). |
| 2008 | Hsieh, W. J.; Hsieh, S. C.; Chen, C. C.; Wang, F. F. (2008, May). Human DDA3 is an oncoportein down–regulated by p53 and DNA damage. Biochem Biophys Res Commun, 369(2):567-72. (SCI). |
| 2007 | Hsieh, P. C.; Chang, J. C.; Sun, W. T.; Hsieh, S. C.; Wang, M. C.; Wang, F. F. (2007, Jul). p53 downstream target DDA3 is a novel microtubule-associated protein that interacts with end-binding protein EB3 and activates beta-catenin pathway. Oncogene, 26:4928-4940. (SCI). |
| 2006 | Hsieh, S. C.; Wang, F. F.; Lin, C. S.; Chen, Y. J.; Hung, S. C.; Wang, Y. J. (2006, Aug). The internalized CdSe/ZnS quantum dots impair the chondrogenesis of bone marrow mesenchymal stem cells. J Biomed Mater Res B Appl Biomater, 79B:95-101. (SCI). |
| 2006 | Hsieh, S. C.; Wang, F. F.; Hung, S. C.; Chen, Y. J.; Wang, Y. J. (2006, Mar). The inhibition of osteogenesis with human bone marrow mesenchymal stem cells by CdSe/ZnS quantum dot labels. Biomaterials, 27:1656-1664. (SCI). |
| 2002 | Tang, P. P.; Hsieh, S. C.; Wang, F. F. (2002, Nov). Modulation of caspase activation and p27(Kip1) degradation in the p53-induced apoptosis in IW32 erythroleukemia cells. Cell signaling, 14(11):961-968. (SCI). |
| 2002 | Hsieh, S. C.; Lo, P. K.; Wang, F. F. (2002, May). Mouse DDA3 gene is a direct transcriptional target of p53 and p73. Oncogene, 21(19):3050-3057. (SCI). |
| 2014 | Lo, W.Y., Sheen, L.Y., Lo, Y. C., Hsieh, S. C.（2014年02月）。The Effects of Blackcurrent on Anti-inflammation and Prevention of Allergic Respiratory Diseases Syndrom。台灣農化學與食品科學，52(1): 25-30。 |
| 2012 | Pua, X. H.; Lee, M. C.; Hsieh, S. C.; Yu, T. C.; Chen, K. C.（2012年12月）。Conceptual design of an industrial-scale plant for ethanol production form taro waste。臺灣農業化學與食品科學，51 (4, 5, 6): 176。 |
| 2019 | 葉昱德、練冠霆、謝淑貞. (2019, Mar). 中國橄欖萃取物對於大鼠在高脂飲食合併低劑量鏈佐黴素所誘導的代謝失調之影響. 機能性食品改善代謝異常與老化之國際研討會, 台北,台灣. |
| 2018 | 鍾頡、謝淑貞. (2018, Nov). Developing Adlay-Functional products for preventing metabolic syndrome by optimization of in vitro starch digestibility. ICC international conference-Grains for wellbeing. |
| 2018 | 戴君倩、謝淑貞. (2018, Aug). Developing Adlay-Functional products for preventing metabolic syndrome based on optimized in vitro starch digestibility assay. 兩岸三地食品安全與健康研討會. |
| 2018 | 戴君倩、謝淑貞. (2018, May). 優化澱粉體外消化方法學以開發改善代謝症候群之即食產品. 台灣營養學會第44屆年會暨學術研討會, 台北,台灣. |
| 2018 | 黃炘雯、謝淑貞、呂廷璋. (2018, Mar). 臺灣烏龍茶水溶性多醣化結構與對巨噬細胞試驗的調節性質. 食品科技學會國際研討會, 台北,台灣. |
| 2018 | 李婉君、鍾頡、謝淑貞. (2018, Mar). 不同加工條件對糙薏仁澱粉消化特性之影響及開發具改善代謝症候功效之糙薏仁產品. 食品科技學會國際研討會, 台北,台灣. |
| 2017 | Hsieh, C. C.; Hsu, S. M.; Hsieh, S. C.; (2017, Aug). Ergostatrien-3β-ol Projects Hepatic Ischemia/Reperfusion Induced Liver Damage in Rats. Biomaterials International 2017 conference, Fukuoka ,Japan. |
| 2017 | Tseng, Y. H.; Hsieh, S. C.; (2017, Aug). Construction of PCV2 Probiotic Oral Vaccine. Biomaterials International 2017 conference, Fukuoka ,Japan. |
| 2016 | Hsieh, S. C.; Kao, Y. H.; (2016, Nov). Study on mechanisms underlying the preventive effects of the Chinese olive ethanol extract on modulation of hyperglycemia and hypercholesterolemia in rat model. JAACT(the 29th Annual and International Meeting of Japanese Association for Animal Cell Technology), Japan. |
| 2015 | Chao, T. Y.; Hsieh, S. C.; Lin, J. H.; (2015, Oct). The WWP1 Gene is a Potential Molecular Target of Human Oral Cancer. NAPA (The 6th International conference on Nutrition and Physical Activity), 台北,台灣. |
| 2015 | 莊莎莎、林佩吟、王如邦、謝淑貞、呂廷璋、羅翊禎. (2015, Dec). 羅漢果皂苷的製備及純化. 食品科技學會年會, 台北,台灣. |
| 2015 | Zheng, Y. H.; Hsieh C. C.; Hsieh, S. C.; (2015, Mar). Protective effects of the extract from longan flower against hepatic ischemia/reperfusion injury in rats. 保健食品學會年會, 台北,台灣. |
| 2014 | Yeh, T. Y.; Hsieh, C. C.; Yu, Y. J.; Hsieh, S. C.; (2014, Nov). Bracteanolide A attenuates hepatic ischemia/reperfusion injury in rats through its anti-oxidation activity. ASMRM, Taipei, Taiwan. |
| 2013 | Wang, C. H.; Lu, T. J.; Hsieh, S. C.; (2013, Oct). Establishment and evaluation of reporter platform for screening food factors with ability to regulate inflammation signaling. 東亞檢測專業技術與機能性食品評估研討會. |
| 2013 | Yeh, Y. T.; Chen, Y. A.; Hsieh, S. C.; (2013, May). Characterization of the anti-inflammation and anti-tumor effects of Chinese olive via cell-based platforms. Conference of Traditional Chinese Medicine on Health, Taipei, Taiwan. |
| 2012 | Wang, C. H.; Hsieh, W. J.; Lu, T. J.; Wan, H. C.; Hsieh, S. C.; (2012, Jul). Establishment and Evaluation of reporter Platform for Screening Health Food with Anti-inflammation Ability. International Conference on Nutrition and Food Sciences, 新加坡. NSC 99-2313-B-002-037-MY2.（本人為通訊作者） |
| 2012 | Hsieh, W. J.; Chiou, S. T., Pan, M. H.; Wang, H. C.; Hsieh, S. C.; (2012, Jul). Establishment and Evaluation of Cell-based Platform for Screening Health Food with Anti-inflammation Ability. 保健食品學會年會, 高雄,台灣. |
| 2011 | Lin, H. Y.; Liao, C. C.; Hwang, L. S.; Wu L. Y.; Hsieh, S. C.; (2011, Oct). The Proteomic Based Mechanism Study Governing the Longan (Dimocarpus longans Lour.) Flower Water Extract-mediated Prevention of Metabolic Syndrome in A High Fructose-fed Rat Model. ICoFF, Taipei, Taiwan. |
| 2011 | Hsieh, C. C.; Liao, C. C.; Hwang, L. S.; Wu L. Y.; Wu, Y. L.; Hsieh, S. C.; (2011, Oct). Proteomic Analysis of Fructose-Induced Metabolic Syndrome in Rats. ICoFF, Taipei, Taiwan. |
| 2011 | Hiseh, S.C.; Chiu, H. Y.; Hsu, Y. L.; Hunag, H. P.;(2011, Jun). Case reports: the effect of probiotics on canine atopic dermatitis. IPC, 斯洛伐克，科希Slovakia Kosice. |
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