Login NTU Food Science & Tech.
Login NTU Food Science & Tech.
| Job Title | Assistant Professor |
|---|---|
| Name | Ming-Hsu Chen |
| Office Tel No. | 02-3366-1838 |
| Education | Ph.D, Department of Agricultural and Biological Engineering, University of Illinois, USA |
| Research Expertise | Food Engineering, Biochemical Engineering, Process Design, Dietary Fiber Production, Gut Microbiome |
| PUBLICATIONS | |
| 2025 | Zhao, S., Zhong, Y., Du, J., Chen, M.-H.*, 2025. Source of plant proteins diverts colonic fermentation of wheat arabinoxylan. LWT-Food Science and Technology, 236, 118664. |
| 2025 | Piccolo, B.D. †, Chen, M.-H. †, Lan, R.S., Moody, B., Yao, T., Huang, T.-Y., Pack, L., Adams, S.H., Lindemann, S.R., 2025. Xenometabolomics reveals metabolic functional guilds unique to specific inulin subtypes in human gut microbiota cultures. mSystems, e01031-25. |
| 2024 | Zhao, S., Lau, R., Chen, M.-H.*, 2024. Influence of chain length on the colonic fermentation of xylooligosaccharides. Carbohydrate Polymers, 331, 121869. |
| 2023 | Zhao, S., Lau, R., Zhong, Y., Chen, M.-H.*, 2023. Lactate cross-feeding between Bifidobacterium species and Megasphaera indica contributes to butyrate formation in the human colonic environment. Applied and Environmental Microbiology, 90(1), e01019-e01023. |
| 2023 | Yao, T., Deemter, D.G., Chen, M.-H., Reuhs, B.L., Hamaker, B.R., Lindemann, S.R., 2023. Differences in fine arabinoxylan structures govern microbial selection and competition among human gut microbiota. Carbohydrate Polymers, 316, 121039. |
| 2023 | Zhao, L., Chen, M.-H., Bi, X., Du, J., 2023. Physiochemical properties, structural characteristics and in vitro digestion of brown rice-pea protein isolate blend treated by microbial transglutaminase. Food Hydrocolloids, 141, 108673. |
| 2022 | Nasir, A., Ahmad, W., Sattar, F., Ashfaq, I., Lindemann, S.R., Chen, M.-H., Van den Ende, W., Oner, E.T., Kirtel, O., Khaliq, S., Ghauri, M.A., Anwar, M.A., 2022. Production of a high molecular weight levan by Bacillus paralicheniformis, an industrially and agriculturally important isolate from the buffalo grass rhizosphere. Antonie Van Leeuwenhoek, 115 (9), 1101-1112. |
| 2022 | Ahmad, W., Nasir, A., Sattar, F., Ashfaq, I., Chen, M.-H., Hayat, A., Rehman, M., Zhao, S., Khaliq, S., Ghauri, M.A., Anwar, M.A., 2022. Production of bimodal molecular weight levan by a Lactobacillus reuteri isolate from fish gut. Folia Microbiologica, 67, 21-31. |
| 2021 | Zhao, S., Dien, B.S., Lindemann, S.R., Chen, M.-H.*, 2021. Controlling autohydrolysis conditions to produce xylan-derived fibers that modulate gut microbiota responses and metabolic outputs. Carbohydrate Polymers, 271, 118418. |
| 2021 | Romero, A.M., Yao, T., Chen, M.-H., Oles, R., Lindemann, S.R*., 2021. Fine carbohydrate structure governs the structure and function of human gut microbiota independently of variation in glycosyl residue composition. Nutrients, 13, 2924. |
| 2020 | Yao, T., Chen, M.-H., Lindemann, S.R., 2020. Structurally complex carbohydrates maintain diversity in gut-derived microbial consortia under high dilution pressure. FEMS Microbiology Ecology, 96, 1-16. |
| 2020 | Nasir, A., Sattar, F., Ashfaq, I., Lindemann, S.R., Chen, M.-H., Van den Ende, W., Ӧner, E.T., Kirtel, O., Khaliq, S., Ghauri, A., Anwas, M.A., 2020. Production and characterization of a high molecular weight levan and fructooligosaccharides from a rhizospheric isolate of Bacillus aryabhattai. LWT-Food Science and Technology, 123, 109093. |
| 2017 | Chen, M.-H., Kim, S.M., Raab, R.M., Li, X., Singh, V., 2017. Heterologous expression of thermoregulated xylanases in switchgrass reduces the exogenous enzyme required for saccharification. Biomass & Bioenergy, 107, 305-310. |
| 2016 | Chen, M.-H., Swanson, K.S., Fahey, G.C.Jr., Dien, B.S., Beloshapka, A.N., Bauer, L.L., Rausch, K.D., Tumbleson, M.E., Singh, V., 2016. In vitro fermentation of xylooligosaccharides from Miscanthus x giganteus by human fecal microbiota. Journal of Agricultural and Food Chemistry, 64, 262-267. |
| 2016 | Chen, M.-H., Bowman, M.J., Cotta, M.A., Dien, B.S., Iten, L.B., Whitehead, T.R., Rausch, K.D., Tumbleson, M.E., Singh, V., 2016. Miscanthus x giganteus xylooligosaccharides: purification and fermentation. Carbohydrate Polymers, 140, 96-103. |
| 2015 | Chen, M.-H. †, Rajan, K. †, Carrier, D.J., Singh, V., 2015. Separation of xylose oligomers from autohydrolyzed Miscanthus x giganteus using centrifugal partition chromatography. Food and Bioproducts Processing, 95, 125-132. |
| 2015 | Huang, H., Nasib, Q., Chen, M.-H., Liu, W., Singh, V., 2015. Ethanol production from food waste at high solids content with vacuum recovery technology. Journal of Agricultural and Food Chemistry, 63, 2760-2766. |
| 2014 | Chen, M.-H., Dien, B.S., Vincent, M.L., Below, F.E., Singh, V., 2014. Effect of harvest maturity on carbohydrates for ethanol production from sugar enhanced temperate x tropical maize hybrid. Industrial Crops and Products, 60, 266-272. |
| 2014 | Chen, M.-H., Bowman, M., Dien, B.S., Rausch, K.D., Tumbleson, M.E., Singh, V., 2014. Autohydrolysis of Miscanthus x giganteus for the production of xylooligosaccharides (XOS): kinetics, characterization and recovery. Bioresource Technology, 155, 359-365. |
| 2013 | Chen, M.-H., Kaur, P., Dien, B., Below, F., Vincent, M., Singh, V., 2013. Use of tropical maize for bioethanol production. World Journal of Microbiology and Biotechnology, 29, 1509-1515. |
| 2009 | Chan, Y.-H., Chiang, M.-F., Tsai, Y.-C., Su, S.-T., Chen, M.-H., Hou, M.-S., Lin, K.-I, 2009. Absence of the transcriptional repressor Blimp-1 in hematopoietic lineages reveals its role in dendritic cell homeostatic development and function. Journal of Immunology, 183, 7039-7046. |
| (*Corresponding author; †Co-first author) | |
| CONFERENCE ABSTRACTS & POSTERS (2021-2025) | |
| 2025 | Lu, S.-M., Chiao, Y.-W., Chen, M.-H.*, 2025. Acetyl modifications alter the colonic fermentation of plant xylan. FEMS MICRO 2025. July 14-17, Milan, Italy. (flash talk & poster; Abstract ID: 668) |
| 2025 | Chiao, Y.-W., Lu, S.-M., Chen, M.-H.*, 2025. Exploring the influence of arabinofuranoside patterns on the colonic fermentation of wheat arabinoxylan. FEMS MICRO 2025. July 14-17, Milan, Italy. (flash talk & poster; Abstract ID: 731) |
| 2025 | Lu, S.-M., Chiao, Y.-W., Chen, M.-H.*, 2025. The role of acetylation in modulating colonic fermentation of plant xylan. ASM Microbe 2025. June 19-23, Los Angeles, California, USA. (Abstract ID: 2969) |
| 2025 | Chiao, Y.-W., Lu, S.-M., Chen, M.-H.*, 2025. Structural modifications of wheat arabinoxylan influence human gut microbiota and metabolic profiles. ASM Microbe 2025. June 19-23, Los Angeles, California, USA. (Abstract ID: 2971) |
| 2024 | Lu, S.-M., Chiao, Y.-W., Chen, M.-H.*, 2024. Impact of degree of acetylation on the colonic fermentation of plant xylan. ICC International Conference. November 25-28, Taipei, Taiwan. |
| 2024 | Zhao, S., Lau, R., Chen, M.-H.*, 2024. Exploring the impact of xylooligosaccharide chain length on modulating human gut microbiota. AIChE Annual Meeting. October 27-31, San Diego, California, USA. |
| 2024 | Zhao, S., Zhong, Y., Chen, M.-H.*, 2024. Employing sequential passage approach to illustrate the microbial consortia responsible for edible gum degradation in the human colon. ASM Microbe 2024. June 13-17, Atlanta, Georgia, USA. (Abstract ID: 4511) |
| 2024 | Zhao, S., Lau, R., Chen, M.-H.*, 2024. Xylooligosaccharides with differential chain length divert the succession dynamics of gut-derived microbial consortia. ASM Microbe 2024. June 13-17, Atlanta, Georgia, USA. (Abstract ID: 4917) |
| 2023 | Huang, H.-Y., Hsieh, C.C., Huang, H.-C., Chen, M.-H., Cheng, K.-C.*, 2023. Developing chitosan particles as biocompatible carrier. ACS Fall 2023. August 13-17, San Francisco, USA. (Abstract ID: 3913044) |
| 2023 | Zhao, S., Lau, R., Chen, M.-H.*, 2023. Differential chain length in xylan-derived fibers drive the divergence in gut-derived microbial consortia. FEMS 2023. July 9-13, Hamburg, Germany. (Abstract ID: 4183) |
| 2023 | Zhao, S., Lau, R., Chen, M.-H.*, 2023. Trophic interactions between Bifidobacterium spp. and the butyrogenic gut commensal Megasphaera elsdenii. FEMS 2023. July 9-13, Hamburg, Germany. (Abstract ID: 3520) (Awarded Student Congress Attendance Grant) |
| 2023 | Zhao, S., Lau, R., Chen, M.-H.*, 2023. Determination of chain length influence on the colonic fermentation of xylooligosaccharides. ASM Microbe 2023. June 15-19, Houston, Texas, USA. (Abstract ID: 5066) |
| 2023 | Zhao, S., Lau, R., Chen, M.-H.*, 2023. Metabolic cross-feeding between Bifidobacterium spp. and Megasphaera elsdenii contribute to butyrate formation in the colonic environment. ASM Microbe 2023. June 15-19, Houston, Texas, USA. (Abstract ID: 4903) |
| 2022 | Zhao, S., Chen, M.-H.*, 2022. Molecular size variations of xylo-polysaccharides and xylo-oligosaccharides produced by controlling autohydrolysis severities determine gut microbiota responses and metabolic fate. 21st IUFoST World Congress. October 31-November 3, Singapore. |
| 2022 | Zhao, S., Zhong, Y., Du J., Chen, M.-H.*, 2022. Effect of undigested plant proteins on human gut microbiota responses: an in vitro study simulating a wheat-based diet. 21st IUFoST World Congress. October 31-November 3, Singapore. |
| ORAL PRESENTATIONS (2021-2025) | |
| 2023 | Chen, M.-H., 2023. Depicting the colonic degradation of dietary fiber: toward quality enhancement of food materials. Annual Meeting of Agricultural Chemical Society of Taiwan. Taipei, Taiwan. June 28. (Invited presentation) |
| 2022 | Chen, M.-H., 2022. Depicting the microbial interactions of bifidobacteria in the colonic environment: toward rational design of probiotic products. Annual Meeting of TALAB. New Taipei City, Taiwan. December 23. (Invited presentation) |
| 2022 | Chen, M.-H., 2022. Future food: developing dietary fiber supplements to target consistent gut microbiota response. 2022 BIO-Asia-Taiwan. Taipei, Taiwan. July 29. |
| 2022 | Chen, M.-H., 2022. Developing dietary fiber products to deliver predictive health benefits. 2022 National Taiwan University X Israel Partners Workshop. Online. May 18. |
| 2021 | Chen, M.-H., Zhao, S., 2021. Beechwood xylan-derived dietary fibers that are produced by an autohydrolysis process govern gut microbiome responses and metabolic outputs. Food Science and Technology Global Conference 2021. Singapore. April 27. |
| REGIONAL CONFERENCES (2024-2025) | |
| 2025 | 呂素妹、焦淯汶、陳明煦 (2025年6月)。Impact of Degree of Acetylation on the Colonic Fermentation of Plant Xylan。台灣農業化學會 114 年度研討會，國立臺灣大學，臺北市。[口頭競賽組優勝] |
| 2025 | 焦淯汶、呂素妹、陳明煦 (2025年6月)。Altering the furanoside patterns of wheat arabinoxylan drives distinct responses in human gut microbiota and metabolic formation。台灣農業化學會 114 年度研討會，國立臺灣大學，臺北市。[壁報競賽組佳作] |
| 2025 | 游翊琪、陳明煦、林欣平、鄭光成 (2025年6月)。Eudragit® modified foaming bacterial cellulose for active packaging applications。台灣農業化學會 114 年度研討會，國立臺灣大學，臺北市。[壁報競賽組優勝] |
| 2024 |
呂素妹、焦淯汶、陳明煦 (2024年11月)。Acetyl substitutions dominate the colonic degradation of plant xylan。台灣食品科技學會第54次會員大會暨研討 會，輔仁大學，新北市。 |
| 2024 | 焦淯汶、呂素妹、陳明煦 (2024年11月)。Exploring enzymatic modification of wheat arabinoxylan and its influence on human gut microbial communities。台灣食品科技學會第54次會員大會暨研討會，輔仁大學，新北市。 |
| Source | Project Title | Role | Year |
| Taiwan | |||
| National Science and Technology Council | Depicting the impact of fine structural difference of xylooligosaccharides on the human gut microbiota: exploring the modification of arabinofuranosides | PI | 2025-2026 |
| National Science and Technology Council | Depicting the impact of fine structural difference of xylooligosaccharides on the human gut microbiota: exploring the role of O-acetyl substitutions | PI | 2024-2025 |
| National Science and Technology Council | Depicting the impact of fine structural difference of xylooligosaccharides on the human gut microbiota: towards rational design of dietary fiber products | PI | 2023-2024 |
| Singapore | |||
| Singapore Food Story R&D Programme | A sustainable bio-platform for high quality microbial protein production | Co-PI | 2021-2022 |
| Singapore Food Agency | Modification of brown rice protein isolate using microbial transglutaminases: functional property enhancement and nutritional evaluation | Co-PI | 2021-2022 |
| MOE AcRF Tier 1 | Inulin colonic digestion: key fermenting microorganisms, microbial interactions, and metabolic output | PI | 2019-2022 |
| NTU Start-Up Grant | Deciphering microbial interactions during nondigestible carbohydrate fermentation and determining their influence on human health | PI | 2019-2021 |
| Period |
|---|
| Current Members | ||
| Ming-Hsu Chen (陳明煦) | ||
| Ming Shan Lin (林明杉) | ||
| Zi-Feng Li (李子鳳) | ||
| Abigail Chua (蔡寶珠) | ||
| You-Kai Kao (高宥鎧) | ||
| Ying-Hsi Tsai (蔡迎希) | ||
| Alumni | ||
| Name | Degree | Thesis Title |
| Yu-Wen Chiao (焦淯汶) | M.S. (2025) | Altering the furanoside patterns of wheat arabinoxylan drives distinct responses in human gut microbiota and metabolic formation |
|
Su-Mei Lu (呂素妹) |
M.S. (2025) | Impact of degree of acetylation on the colonic degradation of plant xylan |
| Sainan Zhao | Ph.D. (2024) | Beechwood xylan-derived dietary fibers: The production, structural properties, and mechanisms to modulate human gut microbiota |
| Alumni_Co-supervision | ||
| Name | Degree | Thesis Title |
|
Hong-Yi Huang (黃宏毅) |
M.S. (2023) | Developing chitosan microparticles as carriers for fermented Chenopodium formosanum extract to ameliorate PM2.5-induced ROS production |
| School Name | Department | Degree | Duration |
|---|---|---|---|
| University of Illinois at Urbana-Champaign | Department of Agricultural and Biological Engineering | Ph.D. | 2010.08 ~ 2015.05 |
| National Taiwan University | Institute of Microbiology and Biochemistry | M.S. | 2004.09 ~ 2006.06 |
| National Taiwan University | Department of Biochemical Science and Technology | B.S. | 2000.09 ~ 2004.06 |
| Organization Title | Department | Job Title | Duration |
|---|---|---|---|
| National Taiwan University | Institute of Food Science and Technology | Assistant Professor | 2022.02 ~ Up to today |
| Nanyang Technological University | School of Chemical and Biomedical Engineering | Assistant Professor | 2019.01 ~ 2022.02 |
| Purdue University | Department of Food Science/Whistler Center for Carbohydrate Research | Postdoctoral Research Associate | 2017.08 ~ 2019.01 |
| University of Illinois at Urbana-Champaign | Department of Agricultural and Biological Engineering | Postdoctoral Research Associate | 2015.04 ~ 2017.06 |
| Academia Sinica | Genomics Research Center | Research Assistant | 2008.08 ~ 2009.08 |
| Honors and Awards | |
| 2014 | Tau Beta Pi - The Honor Society of Engineering |
| 2013 | Gamma Sigma Delta - The Honor Society of Agriculture |
| 2013 | Alpha Epsilon - The Honor Society of Agricultural, Food, and Biological Engineering |
| 2006 | The Deans’ Award, College of Life Science, National Taiwan University |
| Honors and Awards-Research Team | |
| 2025 | Yu-Wen Chiao (焦淯汶)- Honorable Mention Award of Poster Presentation Competition, the 63rd Annual Meeting of the Agricultural Chemical Society of Taiwan |
| 2025 | Su-Mei Lu (呂素妹)- Winner of Oral Presentation Competition, the 63rd Annual Meeting of the Agricultural Chemical Society of Taiwan |
| 2025 | Zi-Feng Li (李子鳳)- Professor Roch-Chui Yu Memorial Scholarship |
| 2024 | Yu-Wen Chiao (焦淯汶)-Professor Roch-Chui Yu Memorial Scholarship |
| 2024 | Su-Mei Lu (呂素妹)-Professor Wei-Hsien Chang Memorial Scholarship |
| 2023 | Sainan Zhao-FEMS Congress Attendance Grant |
| 2023 | Sainan Zhao- Women in Engineering, Science, and Technology (WiEST) Development Grant, Nanyang Technological University, Singapore |
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